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Investigation on Association of ESR2 as a Candidate Gene for Boar sperm motility and kinematic characteristics

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한국동물생명공학회(구 한국수정란이식학회) (Journal of Animal Reproduction & Biotechnology)
초록

Estrogen receptor 2 (ESR2) is involved in oestrogen-related apoptosis in cell cycle spermatogenesis but their effects have not yet confirmed in pig. Therefore, this study was performed to investigatetheir association with semen motility and kinematic characteristics. DNA samples from 126 Duroc pigs with records of sperm motility and kinematic characteristics [Total motile spermatozoa (MOT), Curvilinear velocity(VCL), Straight-line velocity(VSL), the ratio between VSL and VCL(LIN), Amplitude of Lateral Head displacement(ALH)] were used in present study. A single nucleotide polymorphism (g.35547A>G) was associated with MOT, VCL, VAP and ALH in Duroc population (p < 0.05). Therefore, we suggest that the porcine ESR2 may be used as a molecular marker for Duroc boar semen quality, although its functional effect was not clear yet. These results will improve the understanding of the functions of the ESR2 in spermatogenesis within the reproductive tracts, and will shed light on ESR2 as a candidate gene in the selection of good sperm quality boars.

저자
  • Mi Jin Lee(National Institute of Animal Science, Rural Development Adminstration)
  • Jeong A Kim(National Institute of Animal Science, Rural Development Adminstration)
  • Eun seok Cho(National Institute of Animal Science, Rural Development Adminstration)
  • Kyu Ho Cho(National Institute of Animal Science, Rural Development Adminstration)
  • Hak-Jae Chung(National Institute of Animal Science, Rural Development Adminstration)
  • Tae Jeong Choi(National Institute of Animal Science, Rural Development Adminstration)
  • Sun-Young Baek(National Institute of Animal Science, Rural Development Adminstration)
  • Doo-wan Kim(National Institute of Animal Science, Rural Development Adminstration)
  • Young Sin Kim(National Institute of Animal Science, Rural Development Adminstration)