In order to reduce roadside and indoor air pollution for volatile organic compounds VOC), it may be necessary to apply photocatalyst-coated construction materials. This study evaluated the technical feasibility of the application of TiO2 photocatalysis for the removal of VOC present in roadside or indoor air. The photocatalytic removal of five target VOC was investigated: benzene, toluene, ethyl benzene and o,m,p-xylenes. Variables tested for the current study included ultraviolet(UV) light intensity coating materials, relative humidity (RH), and input concentrations. Prior to performing the parameter tests, adsorption of VOC onto the current experiment was surveyed, and no adsorption was observed. Stronger UV intensity provided higher photocatalytic destruction(PCD) efficiency of the target compounds. For higher humidity, higher PCD efficiency was observed. The PCD efficiency depended on coating material. Contrary to certain previous findings, lower PCD efficiencies were observed for the experimental condition of higher input concentrations. The current findings suggested that the four parameters tested in the present study should be considered for the application of photocatalyst-coated construction materials in cleaning VOC of roadside or indoor air.