Marine ecosystems are frequently exposed to a variety of chronic and acute pollutants derived from anthropogenic production and consumption activities. Mussels are sessile (can provide location-specific information), medium-sized (have enough tissue matrix for chemical analysis) filter-feeders (show accumulation of pollutant chemicals from seawater). These biological and ecological characteristics make mussels virtually ideal for pollution monitoring. In this study, Korean mussels (Mytilus coruscus) were collected from nine different sites situated along the coasts of the western sea to the eastern sea of Korea in 2017. Total mercury concentration was highest (mean ± standard error, 92.7 ± 3.5 ng/g dry) on Baengnyeongdo Island in the western sea, and the sites in the southern sea showed the lowest mean concentrations (42.3 - 44.5 ng/g dry). These results were discussed in terms of possible pollution sources.