In this paper, an experimental study on the data compression sensing technique optimized by Northridge earthquake waveform was performed to efficiently obtain the dynamic response of the civil structure. The optimized compression sensing technique is embedded in the wireless sensing system. Also, the dynamic response(acceleration) of the cable-stayed bridge model was acquired and the validity of the compression sensing technique was evaluated. The data compression sensing technique optimized by Northridge earthquake waveform was able to efficiently obtain the dynamic response of a flexible civil structure under 10Hz.