As CFRP with only a single material shows the various fracture properties, it has been applied to the many areas through the whole industry. The method bonding with adhesive has been recommended to apply the CFRP to structure. But it is inevitable that the mechanical joints with bolt, nut and rivet have been used sometimes. This study investigates the effect that these joints influence the CFRP panel through the analysis result. The analysis models as CFRP panels with the thickness of 5 mm have four kinds of layer angles which are 30°, 45°, 60° and 75°. The fracture property is examined when the pressure by the mechanical joint is applied to the upper panel. As the joint pressure is distributed most effectively in case of the layer angle of 60°, it is shown that this pressure becomes lower and the deformation of panel becomes lowest. On the basis of this study result, it is thought that the foundation data for the design of CFRP structure can be provided and contributed to the safety design of structure.