다양한 촬영 조건의 CT 감쇠 지도가 PET 영상에 영향을 미치는지 알아보기 위하여 다양한 kVp와 mA 조건에서 Uniformity phantom 영상의 신호 강도 (SI; Signal Intensity)와 표준 섭취율 계수 (SUV; Standardized Uptake Value)를 측정하고, CTDI(Computed Tomography Dose Index)를 통해 각 조건에 따른 피폭선량을 측정하였다. 또한 동일한 조건에서 Resolution phantom의 반치폭 (FWHM; Full Width at Half Maximum)을 측정하여 CT의 kVp와 mA에 따른 PET 영상의 화질 변화에 대하여 정량적으로 알아보고자 하였다. 연구 결과, CT의 촬영 조건은 PET 영상에는 영향을 주지 않는 것으로 나타났으나, CT의 촬영 조건이 감소하게 되면 방사선 피폭이 감소하게 되지만 영상에 영향을 미치게 되므로 향후 진단이 가능한 CT 화질을 유지하면서 방사선 피폭을 최소화할 수 있는 양전자 방출 단층 촬영 (PET/CT; Positron Emission Tomograph y / Computed Tomography)의 촬영 조건에 대한 연구가 지속적으로 되어야 할 것이다.

PET-CT improves performance and reduces the time by combining PET and CT of spatial resolution, and uses CT scan for attenuation correction. This study analyzed PET image evaluation. The condition of the tube voltage and current of CT will be changed using. Uniformity phantom and resolution phantom were injected with 37 MBq 18F (fluorine ; 511 keV, half life - 109.7 min), respectively. PET-CT (Biograph, siemens, US) was used to perform emission scan (30 min) and penetration scan. And then the collected image data were reconstructed in OSEM-3D. The same ROI was set on the image data with a analyzer (Vinci 2.54, Germany) and profile was used to analyze and compare spatial resolution and image quality through FWHM and SI. Analyzing profile with pre-defined ROI in each phantom, PET image was not influenced by the change of tube voltage or exposure dose. However, CT image was influenced by tube voltage, but not by exposure dose. When tube voltage was fixed and exposure dose changed, exposure dose changed too, increasing dose value. When exposure dose was fixed at 150 mA and tube voltage was varied, the result was 10.56, 24.6 and 35.61 mGy in each variables (in resolution phantom). In this study, attenuation image showed no significant difference when exposure dose was changed. However, when exposure dose increased, the amount of dose that patient absorbed increased too, which indicates that CT exposure dose should be decreased to minimum to lower the exposure dose that patient absorbs. Therefore future study needs to discuss the conditions that could minimize exposure dose that gets absorbed by patient during PET-CT scan.

ABSTRACT
 Ⅰ. INTRODUCTION
 Ⅱ. MATERIAL AND METHODS
  1. 연구 장비
  2. 연구 방법
  3. 통계 분석
 Ⅲ. RESULT
  1. SI와 SUV의 변화
  2. FWMH 변화
  3. CTDIvol 변화
 Ⅵ. DISCUSSION
 Ⅴ. CONCLUSION
 Reference

• Jae-Yoon Park(인천기독병원 영상의학과) | 박재윤
• Jung-hoon Kim(건양대학교병원 방사선종양학과) | 김정훈
• Yong-Ki Lee(동남보건대학교 방사선과) | 이용기 Corresponding Author