This study aimed to investigate the effects of voice recording as a speaking assignment on Korean EFL nursing students’ speaking confidence and perceptions of speaking assignment. The participants of the study were 22 nursing students who took college English course and were divided into two groups. One was an experimental group performing voice recording assignment for speaking practice during 5 weeks and the other was a control group that did not receive treatment by the researcher. Speaking confidence questionnaire and in-depth interview were used to collect the data in this study. The result of this study showed that there was some statistically significant achievement of the participants’ speaking confidence after speaking assignment of voice recording performed by them. In addition, the participants had positive reaction to the experience of the assignment. This suggests that voice recording assignment encourages students to have their speaking confidence and helps them to overcome speaking difficulties in EFL environment.