Recently, a variety of modeling studies have been conducted to examine the air quality over South Korea during the Korea United States Air Quality (KORUS-AQ) campaign period (May 1 to June 10, 2016). This study investigates the impact of different meteorological initializations on atmospheric modeling results. We conduct several simulations during the KORUS-AQ period using the Weather Research and Forecasting (WRF) model with two different initial datasets, which is FNL of NCEP and ERA5 of ECMWF. Comparing the raw initial data, ERA5 showed better accuracy in the temperature, wind speed, and mixing ratio fields than those of NCEP-FNL. On the other hand, the results of WRF simulations with ERA5 showed better accuracy in the simulated temperature and mixing ratio than those with FNL, except for wind speed. Comparing the nudging efficiency of temperature and wind speed fields, the grid nudging effect on the FNL simulation was larger than that on the ERA5 simulation, but the results of mixing ratio field was the opposite. Overall, WRF simulation with ERA5 data showed a better performance for temperature and mixing ratio simulations than that with FNL data. For wind speed simulation, however, WRF simulation with FNL data indicated more accurate results compared to that with ERA5 data.