In recent years, there have been concerted efforts toward predicting ship maneuvering in shallow water since the majority of ship’s accidents near harbors commonly occur in shallow and restricted waters. Enhancement of ship maneuverability at the design stage is crucial in ensuring that a ship navigates safely. However, though challenging, establishing the mathematical model of ship maneuvering motion is recognized as crucial toward accurately predicting the assessment of maneuverability. This paper focused on a study on sensitivity analysis of the hydrodynamic coefficients on the maneuverability prediction of KVLCC2 in shallow waters. Hydrodynamic coefficients at different water depths were estimated from the experimental results conducted in the square tank at Changwon National University (CWNU). The simulation of standard maneuvering of KVLLC2 in shallow waters was compared with the results of the Free Running Model Test (FRMT) in shallow waters from other institutes. Additionally the sensitivity analysis of all hydrodynamic coefficients was conducted by deviating each hydrodynamic derivative from the experimental results. The standard maneuvering parameters including turning tests and zig-zag maneuvers were conducted at different water depths and their effects on the standard maneuvering parameters were assessed to understand the importance of different derivatives in ship maneuvering in shallow waters.