Probiotics have been shown to benefit human health through their role in improving the health of our body, especially gastrointestinal tracts. Probiotic bacteria are commonly incorporated into a variety of functional foods or drug formulations. Despite the extensive commercial exploitation of probiotic bacteria, there are still major knowledge gaps regarding the precise molecular composition and labeling of products. Several studies have reported issues concerning the accuracy of labeling of commercial probiotic products, including inaccurate taxonomy and cell counting. The study of microbiology and genomics has been accelerated by the invention of new technologies such as next generation sequencing (NGS) and flow cytometry (FACS). Recent many studies showed that NGS and FACS technology can be also applied for quality control of commercial probiotics. Here, we review advantages and limitations of current technologies for quality control of commercial probiotics. Principles and applications of new technologies are also introduced as alternative tools for the same purposes.

Abstract
서 론
본 론
    프로바이오틱스 제품의 라벨 규격
    프로바이오틱스 균주의 분류, 동정
    프로바이오틱스 균주의 유전체 분석
    프로바이오틱스 균주의 정량법
    고체배지 배양을 통한 균주 정량시험법: 배지계수법 (Platecount method)
    비배양 실험을 통한 균주 정량시험법: 유동세포분석법(Flow cytometry)
    복합 균주 제품의 정량시험법
    제품의 오염확인 및 안전성 검사
결 론
요 약
References

• 김병용(㈜천랩 마이크로바이옴연구소) | Byung-Yong Kim (Microbiome Research Centre, ChunLab Inc.) Corresponding author