In this paper, the displacement response to seismic loads was analyzed after installing TMD in spatial structures and high-rise buildings. In the case of a spatial structures, since it exhibits complex dynamic behavior under the influence of various vibration modes, it is not possible to effectively control the seismic response by installing only one TMD, unlike ordinary structures. Therefore, after installing eight TMDs in the structure, the correlation between displacement response and mass ratio was examined while changing the mass. The TMD must be designed to have the same frequency as the structure frequency so that the maximum response reduction effect can be exhibited. It can be confirmed that the most important variable is to select the optimal TMD mass in order to install the TMD on the structure and secure excellent control performance against the earthquake load. As a result of analyzing the TMD mass ratio, in the case of high-rise buildings, a mass ratio of 0.4% to 0.6% is preferable. In spatial structures, it is desirable to select a mass ratio of 0.1% to 0.2%. Because this study is based on the theoretical study based on numerical analysis, in order to design a TMD for a real structure, it is necessary to select within a range that does not affect the safety of the structure.