유기게르마늄(Ge-132, carboxyethylgermanium)에 의한 22가지 젖산균의 성장 효과를 0.01~10mg/m1의 농도로 첨가된 GPYS 액체배지에서 조사하였다. 시험한 대부분의 젖산균은 고농도의 게르마늄에서도 내성이 있었고, 게르마늄의 농도가 높을수록 성장을 더욱 촉진시키는 효과가 나타났다. 게르마늄이 10mg/m1의 농도로 첨가된 GPYS배지에서 Lactococcus factis, Lc. cremoris, Lc. diaceti

The growth of lactic acid bacteria was investigated in liquid broth medium containing organic germanium compound(Ge-132, carboxyethylgermanium sesquioxide) in the range of 0.01 to 10mg/ml. Most of all lactic acid bacteria tested were tolerant and could grow better to the high Ge-132 concentration. However, the growth of Leuconostoc mesenteroides and Pediococcus pentosaceus were inhibited in the presence of 10mg/m1 Ge-132. Among 22 strains tested, lactic acid bacteria that were grown to a high degree(about 2 times) by addition of Ge-132 (10mg/ml)were Lactococcus lactis, Lc. cremoris, Lc. diacetilactis, Enterococcus faecium and Streptococcus faecalis. The growth of these strains were markedly accelerated in the culture medium supplemented with 1.omg/ml Ge-132 The optimal concentration of glucose for growth of Lc. lactic was found to be high in medium containing Ge-132 as compared with the case of control. During cultivation viscosity in culture broths of Lc. lactis and Lc. cremoris was rapidly elevated by adding Ge-132 to medium containing high concentration of glucose, and then decreased after incubation of long time. However, in the cultivation of Lc. diacetilactis, E, faecium and S. faecalis, viscosity of culture broths was not increased, even though Ge-132 was shown to be an effective stimulant of growth.

• Park Seok-Kyu
• Lee Sang-Won
• Takafumi Kasumi