Background: Muscle undergoes change continuously with aging. Sarcopenia, in which muscle mass decrease with aging, is associated with various diseases, the risk of falling, and the deterioration of quality of life. Obesity and sarcopenia also have a synergy effect on the disease of the older adults.
Objects: This study examined the risk factors for sarcopenia, sarcopenic obesity, and sarcopenia without obesity and developed prediction models.
Methods: This machine-learning study used the 2008–2011 Korea National Health and Nutrition Examination Surveys in the analysis. After data curation, 5,563 older participants were selected, of whom 1,169 had sarcopenia, 538 had sarcopenic obesity, and 631 had sarcopenia without obesity; the remaining 4,394 were normal. Decision tree and random forest models were used to identify risk factors.
Results: The risk factors for sarcopenia chosen by both methods were body mass index (BMI) and duration of moderate physical activity; those for sarcopenic obesity were sex, BMI, and duration of moderate physical activity; and those for sarcopenia without obesity were BMI and sex. The areas under the receiver operating characteristic curves of all prediction models exceeded 0.75. BMI could predict sarcopenia-related disease.
Conclusion: Risk factors for sarcopenia-related diseases should be identified and programs for sarcopenia-related disease prevention should be developed. Data-mining research using population data should be conducted to enhance the effectiveness of early treatment for people with sarcopenia-related diseases through predictive models.

INTRODUCTION
MATERIALS AND METHODS
    1. Participants
    2. Sarcopenia and Obesity
    3. Risk Factors Using Machine Learning
    4. Statistical Analysis
RESULTS
    1. Sarcopenia
    2. Sarcopenia Obesity
    3. Sarcopenia Without Obesity
DISCUSSION
CONCLUSIONS
REFERENCES

• Seo-hyun Kim(Department of Physical Therapy, The Graduate School, Yonsei University)
• Chung-hwi Yi(Department of Physical Therapy, College of Software and Digital Healthcare Convergence, Yonsei University) Corresponding Author
• Jin-seok Lim(Department of Physical Therapy, The Graduate School, Yonsei University)