This study examines the trends of domestic and foreign smart industries and discusses safety and security issues. Based on the actual situation survey and interview of the smart factory, we would like to examine the perspectives on risks and threats. We will examine safety and health issues related to new harmful and risk factors that may occur in smart factories and suggest institutional development directions for future safety and health. First, a safety and health-related work environment for smart factory workers is investigated and interviews are conducted. Second, we investigate new risk factors and threats to prevent industrial accidents for workers in smart factories. The purpose of this study is to examine what are the new risk factors in the smart factory. In addition, we will try to find reasonable improvement measures by finding out the risks and threats of smart factories through case studies in advanced countries, on-site interviews and surveys.