Volatile organic compounds (VOCs) are chemicals to which humans are exposed frequently via various mediums, including vehicle emissions that contain fine dust and heavy metals, use of organic solvent building materials, furniture, and smoking. Exposure to high concentrations of VOCs may result in loss of consciousness, paralysis, convulsions, and, in the most severe cases, death. Therefore, the present study investigated the indoor and outdoor concentrations of total volatile organic compounds (TVOC) and five types of VOCs (benzene, toluene, styrene, m,p-xylene, and o-xylene) in apartments, a representative residential environment accounting for ~55% of the housing in the Seoul metropolitan area. The research was conducted over four seasons from May 2020 to February 2021, and the levels of VOC concentrations were analyzed by classifying them by season, weekday/weekend, and indoor/outdoor locations. The seasonal trend in VOC concentrations showed that TVOC concentration was highest in summer, with values of 1630.93 ± 1184.10 μg/m3 and 1610.36 ± 1363.43 μg/m3 for indoor and outdoor environments, respectively. The seasonal trends of the concentrations of the five types of VOCs showed that concentrations of benzene and toluene were highest in spring, the concentrations of m,p-xylene and o-xylene were highest in summer, and the concentration of styrene was highest in winter, irrespective of spatial characteristics such as indoor/outdoor environments. In all four seasons, the indoor concentrations were higher than the outdoor concentrations. These results reveal the spatial and temporal distribution characteristics of the VOCs and so can serve as useful basic data for managing indoor and outdoor levels of VOCs.