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고중성지방혈증으로 인한 급성췌장염과 다른 원인으로 인한 급성췌장염의 임상적 차이에 관한 연구 KCI 등재 SCOPUS

Differences in Clinical Features between Hypertriglyceridemia-Induced Acute Pancreatitis and Other Etiologies of Acute Pancreatitis

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대한췌담도학회지 (Korean Journal of Pancreas and Biliary Tract)
대한췌장담도학회(구 대한췌담도학회) (Korea PancreatoBiliary Association)
초록

Background/Aim: The aim of this study was to compare clinical features of hypertriglyceridemia-induced acute pancreatitis (HTGAP) with those of biliary acute pancreatitis (BAP) and alcoholic acute pancreatitis (AAP), respectively.
Methods: Medical records of patients with acute pancreatitis (AP) who were admitted to our institution from January 2014 to December 2018 were retrospectively reviewed. Disease severity and local complications were evaluated according to the 2012 Revised Atlanta Classification. Systemic complications were evaluated according to the Modified Marshall Scoring System. Results: Of the total 610 patients with AP, those with BAP, AAP, and HTGAP were 310 (50.8%), 144 (23.6%), and 17 (2.8%), respectively. Compared with BAP, HTGAP showed higher proportion of moderately severe acute pancreatitis (MSAP) (64.7% vs. 28.1%, p<0.001) and severe acute pancreatitis (SAP) (17.6% vs. 5.5%, p <0.001). And HTGAP showed more local complications (76.5% vs. 26.8%, p<0.001) and higher recurrence rate (52.9% vs. 6.5%, p <0.001), but there was no significant difference in systemic complications (23.5% vs. 11.6%, p =0.140). Contrarily, there was no significant difference between HTGAP and AAP with respect to disease severity (64.7% vs. 63.9% in MSAP and 17.6% vs. 6.9% in SAP, p =0.181), local complications (76.5% vs. 67.4%, p =0.445), recurrence rate (52.9% vs. 32.6%, p =0.096), and systemic complications (23.5% vs. 11.5%, p =0.233).
Conclusions: HTGAP showed higher disease severity, more local complications, and higher recurrence rate than BAP. However, there was no significant difference in clinical features between HTGAP and BAP.

목차
서 론
방 법
    1. 연구 형태 및 대상자
    2. 정의
    3. 통계 분석
결 과
    1. AP 환자의 기본적 특성 및 임상적 특징
    2. HTGAP와 BAP 환자의 비교
    3. HTG-AP와 AAP 환자의 비교
고 찰
요 약
REFERENCES
저자
  • 김태일(대구가톨릭대학교 의과대학 내과학교실) | Tae Il Kim (Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea)
  • 정한택(대구가톨릭대학교 의과대학 내과학교실) | Han Taek Jeong (Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea)
  • 송정은(대구가톨릭대학교 의과대학 내과학교실) | Jeong Eun Song (Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea)
  • 김호각(대구가톨릭대학교 의과대학 내과학교실) | Ho Gak Kim (Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea)
  • 한지민(대구가톨릭대학교 의과대학 내과학교실) | Jimin Han (Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea) Corresponding author