혈당저하를 위한 천연물복합제를 한의학 처방 및 문헌 등을 기초로 하여 구성하고, 기능성 식품 소재로서의 이용가능성을 조사하기 위하여 추출물의 이화학적 특성을 조사하였다. 천연물복합제 5가지 추출물의 수율은 의 범위로 나타났으며, 총페놀성 화합물 함량은 , 총 플라보노이드 함량은 의 범위로 조사되었다. 특히 2번, 3번 및 5번 복합제에서 1,000 mg% 이상의 높은 함량을 나타내었으며, 전자공여능 또한 이들 복합제에서 높은 활성을 보여주었다.

We prepared five different kinds of herb mixtures prescribed for hypoglycemic effect. And the physicochemical properties of their water extracts were assessed to identify functional materials. Yields were in the range . Total phenolics and flavonoid contents were and , respectively, and herb mixtures No. 2, 3 and 5 showed particularly high levels greater than 1,000 mg%. Electron-donating ability was best in herb mixtures showing high levels of total phenolics and flavonoids. Nitrite-scavenging abilities were more than 70% in herb mixtures No. 2 and 5, and decreased as pH increased. Herb mixture extracts strongly inhibited differentiation of 3T3-L1 fibroblasts, with potencies ranked in the herb mixture order 5, 1, 4, 3, and 2. The five different kinds of herb mixtures prescribed for their hypoglycemic effects may be useful as functional food materials.

• 김정옥
• 김정배
• 김학윤