The medicines for treating osteoporosis currently in use have minor to severe side effects, and can be financially burdensome. Thus, there is a need for prevention and alternative supplement that is relatively inexpensive, and can be easily consumed daily as an alternative dietary therapy. In this study, bone marrow density of the spine and femur of osteoporosis patients were checked before and after consuming complex composed of calcium and magnesium, considered to be the core of bone mineral content. November 2017-November 2021, patients with T-score of less than －2.5 or －1.0 < T-score < －2.5 with history of fractures or recent fractures were enrolled. The data of 60 patients who orally administered Ionized Cal/MagTM Complex were reviewed retrospectively, and it was significantly confirmed that the average value of T-score was up-regulated by 0.5. Additionally, the cumulative dose was observed to have a positive effect, on the improvement of BMD in the 2nd Lumbar and Femur neck. It is expected that better results will be achieved if use of the supplement is continued.

Abstract
서 론
연구대상 및 방법
    1. 연구의 대상 및 조사기간
    2. 연구의 방법
    3. 칼슘/마그네슘 복합체(Ionized Cal/MagTM complex)
    4. 통계분석
결과 및 고찰
    1. Ionized Cal/MagTM complex 복용 전 환자들의 특성
    2. Ionized Cal/MagTM complex 복용 전 후 T-score의 변화
    3. 누적 용량에 따른 골밀도의 변화
    4. 부작용
    5. 식이요법으로써 칼슘 섭취의 보충
요약 및 결론
감사의 글
References

• 신동호(서울성모병원 의사) | Dongho Shin (Medical Doctor, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul 06591, Korea)
• 이동섭(성빈센트병원 비뇨의학과 교수) | Dong Sup Lee (Professor, Dept. of Urology, St. Vincent’s Hospital, The Catholic University of Korea, Seoul 06591, Korea)
• 션리(네이쳐리온 파마 이사) | Sean S Lee (Director, Naturion Pharma, Inc., Los Angeles 90670, CA, U.S.A.)
• 김세웅(서울성모병원 비뇨의학과 교수, 그린메디슨 대표) | Sae Woong Kim (Professor, Dept. of Urology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul 06591, Korea / Chairman, Green Medicine Co., Ltd, Busan 48307, Korea) Corresponding author