In this paper, numerical simulations were conducted to secure both flow distribution and uniform flow discharge through a wall mount type air sterilizer. In order to increase the reliability of the simulation results where there is no well-known validation case for air sterilizer, mesh sensitivity study was performed under the constraint that y+ set to one for k-w SST turbulent modeling for both the air sterilizer and the fan. The installation of various guides and structures was reviewed in the point of flow distribution and pressure drop inside the sterilizer, and the exhaust pressure conditions were predicted to secure uniform flow discharge at outlets. This study has been done based on the computational analysis during the development stage of the air sterilizer, and the results will be verified through physical testing after production of prototype.