In this work, a nanocomposite containing gold (Au) nanofibers decorated iron-metal–organic framework (Fe-MOF) was successfully synthesized for electrochemical detection of acetaminophen (AAP). The as-synthesized Au@Fe-MOF nanocomposite was confirmed by various characterization techniques. Morphological analysis showed that the Au nanofibers with an average size of less than 10 nm were dispersed on the Fe-MOF. Cyclic voltammetric analysis showed that the Au@Fe-MOF nanocomposite showed well-defined redox peaks with higher current than that of GCE and Fe-MOF. The Au@Fe-MOF/ GCE exhibited a linear range, sensitivity, and detection limit of 0.5–18 μM, 4.95 μM/μA/cm2, and 0.12 μM, respectively. The Au@Fe-MOF/GCE showed a very low response for the interference materials. The real sample analysis revealed that the Au@Fe-MOF/GCE showed good recovery towards the AAP in urine and paracetamol. Therefore, the developed sensor can be used for quality control of AAP.

    Abstract
    1 Introduction
    2 Materials and methods
        2.1 Materials
        2.2 Synthesis of Fe-MOF
        2.3 Synthesis Au@Fe-MOF nanocomposite
        2.4 Electrochemical experiments
    3 Results and discussion
    4 Conclusion
    Acknowledgements 
    References

• K. V. Kavya(Department of Nanoscience and Technology, Bharathiar University)
• Dinesh Muthu(Department of Nanoscience and Technology, Bharathiar University)
• Stella Varghese(Department of Nanoscience and Technology, Bharathiar University)
• Dhanaprabhu Pattappan(Department of Nanoscience and Technology, Bharathiar University)
• R. T. Rajendra Kumar(Department of Nanoscience and Technology, Bharathiar University)
• Yuvaraj Haldorai(Department of Nanoscience and Technology, Bharathiar University)