논문 상세보기
pp.90-98
석유 에테르로 인삼지방질 성분을 추출해 낸 소위 탈지인삼을 가지고 기본 식이에 0.5, 1.0 및 3.0% 비율별로 각기 혼합하여 만든 탈지인삼식이로 이유 후 체중 83±4g 웅성백서 130두를 대상으로 4주 또는 8주동안 급식한 후 기본식이로 교체하여 다시 8주 또는 4주동안 급식하여, 교체급식에 의한 흰쥐의 혈청, 간 및 대동맥중의 콜레스테롤함량 변화의 추이를 비교 관찰한 바 다음과 같은 결과를 얻었다. 1. 혈청중 총 콜레스테롤과 유리콜레스테롤 함량은 0.5, 1.0 및 3.0% 탈지인삼식이 급식후 기본식이로 교체하여 급식시 증가되었다. 2. 대동맥중 총 콜레스테롤 함량은 0.5, 1.0 및 3.0% 탈지인삼식이 급식후 기본 식이로 교체하여 급식시 감소되었다. 3. 혈청, 간 및 대동맥 중 유리콜레스테롤 함량은 1.0% 탈지안심식이 급식후 기본식이로 교체하여 급식시 증가되었으나, 혈청과 간중 유리콜레스테롤 함량은 3.0%탈지 인삼식이의 경우 감소되었다.
This study was divised to observe the effects of defatted(by petroleum ether) Korean ginseng on the cholesterol level of Sprague-Dowley Albino male rats by alternating the diet. 130 heads of weaned rats having 83±4g of body weight were fed with each stock diets supplemented with 0.5, 1.0 and 3.0% defatted ginseng powder for 4 or 8 weeks, and after that fed with stock diet only for 8 or 4 weeks. Total cholesterol and free form cholesterol contents in serum, liver and aorta of them were determined, and compared with the each corresponding group which was fed with defatted ginseng control diet for 12 weeks. Total cholesterol and free form cholesterol contents in the serum were increased caused by the alternating diets which was fed on 0.5, 1.0 and 3.0% defatted ginseng diet for 4 and 8 weeks after being fed on stock diet for 8 and 4 weeks, conversely total cholesterol contents in the aorta were decreased by the same alternating diets. Free form cholesterol contents in the serum, liver and aorta of the group which was fed on 1.0% defatted ginseng diet 8 weeks after being fed on stock diet for 4 weeks were increased, but that of the group which was fed alternately on 3.0% defatted ginseng diet were decreased than the corresponding defatted ginseng control diet group.
