논문 상세보기
pp.112-118
Seaweed-derived foods have long been popular in Korea because of their high content of nutrients that are beneficial to the human body. Recently, Korean seaweeds have been used as raw materials to produce new natural products with health benefits. Herein, we compared the antioxidant activity of 16 Korean seaweed extracts to explore their potential utility as health foods. The total phenolic content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of seaweed extracts were determined. We also investigated their ability to protect human diploid fibroblast (HDF) cells against hydrogen peroxide. The results showed that seaweed extracts at a concentration of 100 g/mL did not cause any cell toxicity. Sargassum thunbergii (Jichung-i) had the highest TPC and radical scavenging effects, followed by Porphyra tenera (Gim), Silvetia siliquosa (Tteumbugi), and Sargassum fusiforme (Tot). Hydrogen peroxide increased the production of intracellular reactive oxygen species, while P. tenera (Gim), Saccharina japonica (Dasima), and S. thunbergii (Jichung-i) extracts significantly decreased it. The effect was highest in the S. thunbergii (Jichung-i)-treated HDF cells. These findings indicate that S. thunbergii (Jichung-i) shows promise as a potential antioxidant raw material.
I. 서 론
II. 연구내용 및 방법
1. 실험 재료 및 시약
2. 총 폴리페놀 함량 측정
3. 라디칼 소거능
4. 세포배양
5. 추출 시료의 세포독성평가
6. 항산화능 분석
7. 통계처리
III. 결과 및 고찰
1. 국내 자생 해조류 추출물의 총 폴리페놀 함량과 항산화 효과
2. 피부섬유아세포에서 국내 자생 해조류 추출물의 세포독성반응
3. 피부섬유아세포에서 국내 자생 해조류 추출물의 산화스트레스 억제 반응
IV. 요약 및 결론
Conflict of Interest
References
