논문 상세보기
pp.105-109
본 연구는 지방분해 및 식욕억제 인자로 알려진 암독소 호르몬-L의 체지방 분해작용에 미치는 각국 인삼의 petroleum ether(PE) 추출불의 영향을 비교·관찰하고자 시도하였다. PE에 의해 추출되어진 지질성분의 수율은 고려홍삼, 중국홍삼 및 미국백삼이 각 0.64, 0.47 및 0.58%로 고려홍삼이 가장 높았다. 시험관내에서 PE 추출물의 체지방 분해작용 억제율은 2㎎/㎖ 반응농도에서 고려홍삼, 중국홍삼 및 미국백삼이 각 55.1, 50.0 및 44.9% 였고, 체지방 분해작용 총 억제활성은 각 18, 12 및 13 unit로 역시 고려홍삼이 모두 가장 높았다
This study was devised to observe the inhibitory effects of 3 kinds of petroleum ether extracts(percolation by petroleum ether) from Korean red ginseng, Chinese red ginseng and American white ginseng on a lipolytic action of Toxohormone-L which has been known as lipolytic and anorexigenic factors. Toxohormone-L was obtained by partial purification of the ascites fluid from mice which had been inoculated with sarcoma-180. The yields of petroleum ether extract from Korean red ginseng, Chinese red ginseng and American white ginseng were 0.64, 0.47 and 0.58% respectively, indicating that the yield of Korean red ginseng was the highest. In vitro, at the concentration of 2㎎/㎖, the inhibition rate of lipolysis by the petroleum ether extract of Korean red ginseng, Chinese red ginseng and American white ginseng were 55.1, 50.0 and 44.9% respectively, and the total inhibitory activity per gram of ginseng material were 18, 12 and 13 unit respectively, indicating that the Korean red ginseng was the most effective in the inhibition of the lipolysis.
