Economic globalization and regional economic integration have become the world’s two major trends of the world economy, with most countries pursuing broader economic development of space through the strengthening of national and regional economic and trade ties. The geographic proximity of China and ASEAN nations, both in terms of resources, industrial structure, and industrial and agricultural goods, among other things, is very complimentary, and the growth of economic and trade cooperation has a distinct benefit. Long-term “neighborly and friendly” strategic partnership relationships have provided a solid framework for the growth of economic and trade cooperation. The establishment of the China-ASEAN Free Trade Area can achieve a win-win situation by not only complementing each other and expanding bilateral trade and cooperation on a larger scale, but also strengthening overall competitiveness and its ability to resist risks. Friendly relations between China and ASEAN will be further consolidated and strengthened to improve the Chinese and ASEAN in East Asia and the Asian region’s political status and ability to deal with international affairs. This article proposes solutions to the challenges that exist in the China-ASEAN Free Trade Zone. The establishment of the China-ASEAN Free Trade Area will not only consolidate and strengthen China’s and ASEAN’s already friendly and cooperative relations, but will also further promote China’s and ASEAN’s respective economic development and regional cooperation and competitiveness. Finally, with the construction of the China-ASEAN Free Trade Area, China and ASEAN will enjoy the benefits of economic globalization and regional economic integration even more, face obstacles jointly, and contribute to the growth and stability of Asian and global economies.