This paper presents a strategic adoption model for blockchain technology in nuclear nonproliferation by analysing the implementation of legally binding agreements and leveraging results from governmentleading sectors. Blockchain has been emerging as not only a single promising technology but a foundational one which can be combined with diverse sectors. From the national point of view, it is imperative that the government formulates policy for fostering blockchain-related industries, thereby, gaining a competitive advantage at the national level. Accordingly, the Korean government has established the Blockchain Technology Development and Diffusion Strategies in 2018 and 2020, respectively, to verify the technology by supporting pilot projects for apposite industries, such as customs clearance, transhipment of containers, record-keeping of meat processing, and smart contracts. In addition, the strategies announce to support liaison with regulatory sandbox and cooperation between the projects. Internationally, on the other hand, nuclear nonproliferation imposes the duties of verifying that member states under the NPT and the Safeguards Agreement obey the IAEA mandate, “Atoms for Peace and Development”. Similarly, bilateral nuclear cooperation agreements and administrative arrangements specify reporting obligations for the origin and history records of the Trigger List items. Meanwhile, commercial and industrial secrets and other confidential information of any entities involved have to be securely protected. Provided accompanying activities accomplish the integrity of records and mutual transparency, it brings more credibility, and further, the competitiveness of the state’s nuclear industry. In conclusion, the tasks that the Republic of Korea implements as an exemplary country complying with the nuclear nonproliferation regime have many similarities with the pilot projects that have been or are being carried out under national strategies for fostering blockchain technology elsewhere. This implies that the leveraging of the subsets can derive a new competitive model in blockchain adoption that contributes to the competitiveness of the national nuclear industry due to the advanced nuclear regulations.