There are many Systems, Structures, and Components (SSCs) in Nuclear Power Plants (NPPs). The systems include radiological waste treatment system, spent fuel pool cooling, emergency core cooling systems, etc. The structures include reactor building, piping vaults, radioactive waste storage facilities, etc. The components include valves, pumps, piping segments, etc. Radionuclides exist in some of these SSCs and unplanned release may occur when leaks or spills from them. And also Work Practice (WP) is another reason of unplanned release in NPPs. The WP is defined as an action taken by individuals during maintenance, operational or support activities, which could result in or prevent a spill or leak of a radioactive solid, liquid or gas that has a credible mechanism for contamination of groundwater. According to the results of the Electric Power Research Institute (EPRI) survey, a total of 323 unplanned release event occurred at US NPPs from 1970 to 2014. Among them, 219 events were counted to have occurred at pressurized water reactors (PWRs). In addition, it was confirmed that 41 of the 44 PWR sites (about 93%) in the US, operated at the time of the survey period, had experienced at least one unplanned release events of licensed material which impacted groundwater. This means that the US PWR sites have experienced an average of approximately 5 unplanned release event per site. The source with the most unplanned releases, including SSCs and WP, was miscellaneous systems with a percentage of about 33% (72 events). Miscellaneous systems include pipes, and it was confirmed that unplanned releases mainly occurred in pipes such as the main steam system, condensate and feedwater system, and emergency core cooling system. And the percentage was high in the order of WPs (21%, 45 events), radioactive effluents (20%, 43 events), refueling water storage (8%, 17 events), radioactive waste/material operations (7%, 16 events), spent fuel storage (5%, 12 events), unknown (4%, 9 events), and structures (2%, 5 events). The history of the unplanned release of the US NPPs will be considered when revising major SSCs in the domestic NPP groundwater monitoring program.