Since the Fukushima nuclear accident in 2011, the development of accident tolerant fuel (ATF) has been actively pursued as an alternative to improve the safety of nuclear power plants. In addition, nuclear power plants containing ATF have recently been included as green energy in the 2022 EU taxonomy bill, receiving a lot of attention. Many countries are considering increasing 235U enrichment from 5 to 10 235U % for higher burnup and long cycle operation with ATF improving safety. To utilize ATF, the applicability of fuel storage systems such as new fuel storage vault, Region 1, and Region 2 must be determined. The purpose of this paper is to confirm the applicability of applying ATF, which is being developed in Korea, to the nuclear fuel storage system of Korean nuclear power plants. The nuclear power plant model used in the analysis is APR-1400, a representative Korean nuclear power plant model, and ATF model used in the analysis is Mo microcell UO2 pellet with CrAl coating, which is being developed in Korea. MCNP 6.2 has been used for multiplication factor calculations, and the TRITON/NEWT and ORIGEN-S modules of the SCALE code have been used for depletion calculations. From the analysis results, solutions and additional analysis would be necessary to satisfy criticality regulatory requirements to utilize ATF with increased enrichment.