This study was conducted to collect the patents of microbiome-based treatment technology for pets. An electronic search for microbiome or probiotics in brain nervous system disease was studied using the WINTELIPS database. Patent Cooperation Treaty of Korea, Japan, the EU, the US, and China that were registered by October 31, 2022 were selected in this study. A total of 206 patents were included for final analysis. Since 2016, patent activity has shown an explosive increase in recent years. China is the leading market in this technology field, and Korea has the second-highest market share. To provide the groundwork for the next research and development, we examined the industrial trend of microbiome for brain nervous system diseases in this study using an analysis of patents that have been applied for and registered up to this point. Looking at the overall patent trends by year in the technology field related to treating of brain and nervous system diseases using the microbiome, there was a tendency to repeat increasing and decreasing trends. However, considering 2021 and 2022, which have undisclosed sections, it can be seen that patent activity has tended to increase explosively in recent years, starting in 2016. If related studies use the patent analysis data constructed in this way strategically, it is expected that it will lead to patent registration and the development of new products, ultimately contributing to the revitalization of the companion animal industry.

INTRODUCTION
MATERIALS AND METHODS
    분석대상 특허검색 DB 및 검색 범위
    분석 대상 기술 및 검색식 도출
    유효 특허 선별 기준 및 결과
RESULTS
    특허 기술의 정량분석
    특허 기술의 정성분석
DISSCISSION
References

• Byung-Suk Jeon(Toxicological Evaluation Laboratory, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea)
• Huiyeong Jeong(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea)
• Sohee Jeong(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea)
• Changjong Moon(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea)
• Jong-Hwan Park(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea)
• Sung-Ho Kim(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea) Corresponding author
• Joong-Sun Kim(College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea) Corresponding author