Gold nanoparticles (Au NPs) decorated carbon nanofibers (CNFs) have been prepared by an electrospinning approach and then carbonized. The prepared Au-CNFs were employed to modifying a screen printed electrode (SPE) for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). Au NPs are uniformly dispersed on carbon nanofibers were confirmed by the structure and morphological studies. The modified electrodes were tested in cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) to characterize their electrochemical responses. Compared to bare SPE, the Au-CNFs/SPE had a better sensing response to AA, DA, and UA. The electrochemical oxidation signal of AA, DA and UA are well separated into three distinct peaks with peak potential separation of 280 mV, 159 mV and 439 mV between AA-DA, DA-UA and AA-UA respectively in CV studies and the corresponding peak potential separation in DPV studies are 290 mV, 166 mV and 456 mV. The Au-CNFs/SPE has a wide linear response of AA, DA and UA in DPV analysis over the range of 5–40 μM ( R2 = 0.9984), 2–16 μM ( R2 = 0.9962) and 2–16 μM ( R2 = 0.9983) with corresponding detection limits of 0.9 μM, 0.4 μM and 0.3 μM at S/N = 3, respectively. The developed modified SPE based sensor exhibits excellent reproducibility, stability, and repeatability. The excellent sensing response of Au-CNFs could reveal to a promising approach in electrochemical sensor.

Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid using Au decorated carbon nanofibers modified screen printed electrode
    Abstract
        Graphical abstract
    1 Introduction
    2 Experimental section
        2.1 Materials
        2.2 Preparation of Au NPs decorated CNFs
        2.3 Characterizations of Au NPs decorated CNFs
        2.4 Preparation of Au-CNFs modified SPE electrode
    3 Results and discussion
        3.1 Electrochemical behaviour of Au-CNFsSPE
        3.2 Electrochemical detection of AA, DA, and UA
    4 Conclusion
    References

• P. Sakthivel(Department of Chemistry, Builders Engineering College, Tiruppur 638 108, Tamil Nadu, India)
• K. Ramachandran(Department of Chemistry, Builders Engineering College, Tiruppur 638 108, Tamil Nadu, India)
• K. Maheshvaran(Department of Physics, Kongu Engineering College, Erode 638 060, Tamil Nadu, India)
• T. S. Senthil(Centre for Nanotechnology, Erode Sengunthar Engineering College, Erode 638 057, Tamil Nadu, India)
• P. Manivel(Centre for Nanotechnology, Erode Sengunthar Engineering College, Erode 638 057, Tamil Nadu, India) Corresponding author