This study examines the seismic vulnerability of non-structural components in high-rise buildings by proposing a normalized floor response spectrum (FRS) suitable for practical application. A Bayesian-mode-based method (BMBM) is used to develop the FRS, incorporating both modal amplification effects and the probabilistic variability observed across different building heights and story levels. The resulting spectrum is methodically compared with existing code-based and empirical methods to assess its consistency, conservatism, and relevance to engineering practices. The findings demonstrate that the proposed FRS provides a realistic yet reliable upper-bound estimate of floor accelerations, particularly in the upper stories where modal interactions are significant. This research offers a robust and practical framework for enhancing the seismic design of nonstructural components in vertical structures.