Purpose: This study aims to examine the characteristics and educational outcomes of immersive virtual reality (VR)-based nursing simulation using the integrative review method developed by Whittemore and Knafl. Methods: Data were collected between December 30, 2023, and January 15, 2024. Studies published in English or Korean were included without restrictions of publication year. Searches were conducted in PubMed, Web of Science, EMBASE, CINAHL, RISS, KISS, DBpia, and KoreaMed using combinations of the keywords “‘nursing”, “student*”, “simulation”, “SIM”, “education”, “VR”, and “Virtual reality” to identify relevant articles. Results: Of the 237 studies identified, 11 were included in the analysis, with most conducted in Korea (n=7). In most studies, scenario-based VR was used; the Oculus platform (n=4), the HTC Vive (n=2), and a mobile HMD (n=1). Six studies incorporated handheld controllers, and three haptic sensors. VR groups showed greater improvements in knowledge, engagement, self-confidence, and skill performance than the control groups. Usability ratings were high for accessibility and realism; however, challenges were observed in device operation, especially without technical support. Reported adverse effects included visual fatigue, headache, dizziness, motion sickness, and discomfort when wearing glasses. Conclusions: Immersive VR simulation offers realistic, customizable learning environments, enhancing nursing education, supporting advanced instructional methods, and improving clinical safety and patient-centered competencies. Ongoing efforts in technological standardization, program development, and curricular integration are recommended.