Human errors committed by traffic managers have consistently been identified as one of the major causes of traffic accidents. In fact, these errors are not merely the result of individual negligence but are closely related to the organizational level of safety culture. This study empirically examines the effects of safety-culture factors on the occurrence of human error through a survey of 100 employees from road and railway traffic control centers. Safety culture was categorized into five dimensions: leadership, rule compliance, reporting system, mutual trust, and learning orientation. Human error was defined based on Rasmussen’s generic error-modeling system (GEMS) as slips, mistakes, or violations. The analysis revealed that leadership and reporting system contributed the most significantly in reducing human error, whereas learning orientation and mutual trust show significant effect. Rule compliance is statistically significant but its effect size is relatively limited. This study transcends the classical perspective of regarding managerial human error as an individual fault and demonstrates that the level of organizational safety culture is a decisive factor in error prevention. Furthermore, the findings provide both academic and practical implications by suggesting directions for strengthening safety culture at the level of traffic-safety policy and organizational management.