Oral Epithelial Dysplasia (OED) is an oral potentially malignant disorder that can progress to Oral Squamous Cell Carcinoma (OSCC).
Although higher grades of OED are associated with an increased malignant transformation rate, malignant transformation can occur at
any time even in lower-grade dysplasia due to genetic mutations or microenvironmental changes, making reliance on a single biopsy
risky. This report describes the clinical and histopathological changes observed during the progression of a lesion initially diagnosed
as OED to OSCC, emphasizing the importance of early diagnosis and continuous follow-up.

• 신창걸(경북대학교 치과대학 구강악안면외과학교실) | Chang-Geol Shin (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
• 홍수형(경북대학교 치과대학 구강미생물학교실) | Su-Hyung Hong (Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University)
• 최소영(경북대학교 치과대학 구강악안면외과학교실 및 치의학중개연구소) | So-Young Choi (Department of Oral and Maxillofacial Surgery and ITRD, School of Dentistry, Kyungpook National University) Corresponding author