간행물
대한구강악안면병리학회지 KCI 등재 The Korean Journal of Oral and Maxillofacial Pathology
- 발행기관 대한구강악안면병리학회
- 자료유형 학술지
- 간기 격월간
- ISSN 1225-1577 (Print)2384-0900 (Online)
- 수록기간 1977 ~ 2026
- 주제분류 의약학 > 치의학 의약학 분류의 다른 간행물
- 십진분류KDC 515DDC 610
권호리스트/논문검색
제50권 제3호 (2026년 6월) 3건
1.
2026.06
구독 인증기관 무료, 개인회원 유료
Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare distinctive ulcerative lesion of the oral mucosa that is generally considered to be associated with trauma. Clinically, it may mimic malignant ulcerative lesions, making accurate diagnosis particularly important. This retrospective study analyzed 64 patients diagnosed with TUGSE at the Department of Oral Pathology, Seoul National University Dental Hospital over a 25-year period from 2000 to 2025. Clinical information and histopathologic findings were analyzed through review of medical records and pathological slides. Among the 64 cases, 38 patients (59.4%) were male and 26 (40.6%) were female, with a mean age of 47 years (range, 8–86 years). The tongue was the most commonly affected site, accounting for 37 cases (57.8%), followed by the buccal mucosa and the floor of the mouth. Biting-related trauma was considered the most likely etiologic factor in 22 cases (34.3%). All lesions showed spontaneous healing following biopsy. Histopathologically, all cases demonstrated proliferation of granulation tissue beneath the ulcerated epithelium accompanied by infiltration of chronic inflammatory cells. Prominent eosinophilic infiltration extending deeply into the underlying muscle layer was a characteristic finding. 33.7% of the lesions were initially suspected to be malignant or potentially malignant lesions prior to biopsy, suggesting that histopathologic examination is essential for the accurate diagnosis and appropriate management of TUGSE.
4,000원
2.
2026.06
구독 인증기관 무료, 개인회원 유료
Odontogenic keratocysts (OKCs) are typically intraosseous developmental cysts characterized by specific histopathological features and a relatively high recurrence rate. Peripheral odontogenic keratocysts (POKCs) occurring in soft tissues are extremely rare, with the buccal mucosa representing an exceptionally uncommon site. A 71-year-old male presented with a progressively enlarging mass in the right buccal mucosa. Clinical and radiographic examinations, including panoramic radiography and computed tomography, revealed an 18 mm soft tissue mass without bony involvement. Under a clinical impression of a benign soft tissue cyst, the lesion was surgically enucleated. Histopathological examination revealed a cystic cavity lined by a uniform parakeratinized stratified squamous epithelium with a palisaded hyperchromatic basal cell layer and a corrugated luminal surface, confirming a diagnosis of peripheral odontogenic keratocysts (POKCs). The postoperative course was uneventful, and no clinical signs of recurrence were observed at the 2-year follow-up. Although POKCs in the buccal mucosa are rare, they should be considered in the differential diagnosis of solitary soft tissue masses in this region. Clinical features alone are often non-specific and insufficient for diagnosis; therefore, definitive histopathological confirmation of the parakeratinized epithelial lining is essential for appropriate management and long-term follow-up.
4,000원
3.
2026.06
구독 인증기관 무료, 개인회원 유료
Oral Epithelial Dysplasia (OED) is an oral potentially malignant disorder that can progress to Oral Squamous Cell Carcinoma (OSCC).
Although higher grades of OED are associated with an increased malignant transformation rate, malignant transformation can occur at
any time even in lower-grade dysplasia due to genetic mutations or microenvironmental changes, making reliance on a single biopsy
risky. This report describes the clinical and histopathological changes observed during the progression of a lesion initially diagnosed
as OED to OSCC, emphasizing the importance of early diagnosis and continuous follow-up.
4,000원
