간행물
대한구강악안면병리학회지 KCI 등재 The Korean Journal of Oral and Maxillofacial Pathology
- 발행기관 대한구강악안면병리학회
- 자료유형 학술지
- 간기 격월간
- ISSN 1225-1577 (Print)2384-0900 (Online)
- 수록기간 1977 ~ 2024
- 주제분류 의약학 > 치의학 의약학 분류의 다른 간행물
- 십진분류KDC 515DDC 610
권호리스트/논문검색
제37권 제4호 (2013년 8월) 6건
1.
2013.08
구독 인증기관 무료, 개인회원 유료
Inflammation functions as a double-edged sword against external stimulus. For instance, inflammation can have anti-cancer effect and simultaneously can play cancer-promoting factors. Recent studies have shown that cytokine plays an important role in tumor biology by influencing tumor growth, invasion and metastasis. We classify these cytokines by cancer type and review current knowledge of cytokines in terms of carcinogenesis. Here, we also focus on whether cytokines can act as biomarkers for early detection of oral squamous cell carcinoma (OSCC). This review will provide basis for further approach to study the role of cytokines in carcinogenesis and evaluating the possibilities of cytokines as biomarkers for cancer detection
4,000원
2.
2013.08
구독 인증기관 무료, 개인회원 유료
A 72 years old male complained of gingival ulceration and whitish discoloration on the marginal and attached gingival epithelium of left mandibular premolar and molar area, where a porcelain-fused metal (PFM) crown and an ill-fitting gold crown were applied for 10 years, respectively. Recently he had a cancer phobia due to this whitish lesion unhealed even after intensive anti-inflammatory and antibiotic treatment. In the pathological examination the epithelium was hyperkeratotic and acanthomatous with severe inflammatory reaction, and subsequently its basement membrane was distorted and the intercellular spaces between keratinocytes were widened. Particularly, the nuclei of keratinocytes were elongated in the same direction towards the electric current between the dissimilar metallic crowns of PFM gold. In the immunohistochemistry KL1, β-catenin, and S-100 were strongly positive in the epithelium, but consistently weak for TNFα, HSP-70, and β-defensin-1, -2, -3. On the other hand, PCNA, p53, E-cadherin, and pAKT were rarely positive for the epithelium. Interestingly, the hyperkeratinized and inflamed epithelium was strongly positive for a calcium binding protein (S-100), while it showed almost reduced expression of protective molecules (HSP-70, β-defensin-1, -2, -3, and pAKT). Therefore, it was presumed that this localized lichenoid gingivitis was caused by the galvanic current phenomenon with lower cellular and immunological responses contrary to the ordinary oral lichen planus and leukoplakia
4,000원
3.
2013.08
구독 인증기관 무료, 개인회원 유료
Squamous odontogenic tumor (SOT) is a rare benign neoplasm first described by Pullon et al. in 1975. Clinically and histologically, it is confused with ameloblastoma, carcinoma and local periodontoal disease. We report a case of SOT occuring in a 16-year-old female in the right mandibular angle location associated with an impacted molar
4,000원
4.
2013.08
구독 인증기관 무료, 개인회원 유료
A Warthin’s tumor of major salivary glands, in particular of parotid glands, is a common benign tumor that may occur synchronously or metachronously in the same or contralateral gland. Moreover, epithelial malignance associated with a Warthin’s tumor is extremely rare, and exists in three forms; epidermoid carcinoma, adenocarcinoma, and undifferentiated carcinoma. The reports, related with a case of squamous cell carcinoma arising in a Warthin’s tumor at the parotid gland were reported only additional 3 cases from 1999 to 2010; 30 cases reported up to 1999.[2,4,7] This case report was a extremely rare case where both a primary squamous cell carcinoma and a Warthin's tumor were coexisting in the same
4,000원
5.
2013.08
구독 인증기관 무료, 개인회원 유료
The nasopalatine duct, the most dominant developmental tubule formed by the emergence of premaxilla and both sides of anterior palatal processes. This duct normally disappears in humans but remains latent and provides communication between the oral and nasal cavities in some mammals. However, the duct is obliterated and degenerated before birth in human, thus the persisting or patent nasopalatine duct in postnatal life is considered a developmental anomaly. Two cases of patent nasopalatine duct were presented in this study. Although the ducts were not sectioned longitudinally, they were probably connected each other and contained mucous materials secreted from the associated mucous glands. In the immunohistochemical study the ductal epithelium was consistently positive for the growth-related biomarkers including TGFβ1, c-erbB2, EGFR, CTGF, FGFb, HGF, eiF5A, FAK, and pAKT. And many columnar epithelial cells of the duct were positive for PCNA. Particularly, TNFα was clearly positive in the ductal epithelium together with β-defensin-2, -3 and MMP-3, -9. These findings may imply that the ducts have a growth potential postnatally and also can induce inflammatory reaction. Therefore, it was presumed that the present cases of patent nasopalatine ducts were caused by the latent proliferation of ductal epithelia in the vascular environment of nasopalatine canal without cyst formation, and also suggested that the patent nasopalatine ducts connected with functioning mucous glands were partly open to oral/nasal cavity and should be differentially diagnosed from the nasopalatine duct cyst.
4,000원
6.
2013.08
구독 인증기관 무료, 개인회원 유료
Recently, oteomyelitis from oral and maxillofacial region which is an acute or chronic inflammatory process in medullary spaces or cortical surfaces of bone is uncommon in Korea. And the clinicopatholgic study of osteomyelitis in Korea has been rarely reported. The purpose of this study were to examine the clinicopatholgic analysis of osteomyelitis patients and to apply its results for treatment. Retrospective analysis of 103 cases of osteomyelitis patients treated in the Department of Oral and Maxillofacial Surgery at DKUDH from 1991 to 2000. There was a male predominance with a 2.3:1 ratio. The mean age of onset of disease was almost the same in cases of acute and chronic osteomyelitis: 29.4 years(range 1-81 years). Swelling, pain, pus discharge, and sequestration were main characteristic features of this disease entity. Acute chronic osteomyelitis of the jaws is caused mostly by a bacterial focus(odontogenic disease, periapical lesion, pericoronitis, periodontal disease, postextraction wounds, and infected fractures). It suggested that acute and chronic osteomyelitis could be basically the same disease separated by the arbitrary time limit of 1 month after onset of the disease by a true bacterial infection. And these results could play an role in the diagnosis and treatment of osteomyelitis of the jaws
4,000원
