간행물
대한구강악안면병리학회지 KCI 등재 The Korean Journal of Oral and Maxillofacial Pathology
- 발행기관 대한구강악안면병리학회
- 자료유형 학술지
- 간기 격월간
- ISSN 1225-1577 (Print)2384-0900 (Online)
- 수록기간 1977 ~ 2024
- 주제분류 의약학 > 치의학 의약학 분류의 다른 간행물
- 십진분류KDC 515DDC 610
권호리스트/논문검색
제29권 제6호 (2005년 12월) 6건
1.
2005.12
구독 인증기관 무료, 개인회원 유료
This article desc 1'ibes a pooled analysis 01' Korean indiγ idu a l s with 41 cases 01' metastatic o1'al tumors. The data on this review are based on t he 1'etr ieved published case reports from t he Korean dental and medical li te1'ature between t he years 1983 and 2004, The mean age was 55,2 years and the male to female ratio was 1,9 :1, There were more jaw bone me t astas is than in oral soft tIssues Comparing with the western literatures which report the breast as the most common p rimary s ite, the most common primary s ite was the liver fo llowed by the lung‘ and thyroid, The lung was the most common primary s ite [or t he jawbone metastasis ‘ whereas the liver was for the oral soft tlssues This discrepancy may caused by underestimation or exc lus ion ofthe jawbone in su rveying fo1' the breast tumor metastaslS Anothcr reason is t hat a relat ive ly hi gh incidence rate 이’ hepatocellul ar carcinoma occurs in Ko1'ean, especially in male
4,000원
2.
2005.12
구독 인증기관 무료, 개인회원 유료
The ciga rette smoki ng may act direct ly on the oral mucosal membrane The effects of smoking has many harrnJul effects on the oral cavi ty ‘ s uch as oral cancer. oral Icukoplakia , erythroplakia‘ nicotine stomati tis. ha iry tongue. smoker’s melanosis. acute nec roti zing ulverative gingivitis, gingivitis/periodontitis ‘ treatment of periodontitis. implant surgery a nd den tal cari es. lf pregna nt woman smokes. the tobacco can effect on the both pregnant and embryo/fetus negati ve ly. For the cessation 0 [' smoki ng, the dentists have an important role to play in preve nti ng t he harmful efTects on smoking in the oral cav ity, Conseq uently smoking cou nseling should be as a part of the dentist's job in the de ntal pract ice,
4,000원
3.
2005.12
구독 인증기관 무료, 개인회원 유료
Epitheli a l mesenchymal interaction(EMl) is well known to be essential in eznbryonic deve]opment. wound hea]jng a nd ca rci nogenes is. Th is study was a i med to design in vi tro model for the investigation of protein analysis in epithe li al a ncl mesenchyma l i nteract ion(EMI) . This stucly usecl oral squamous cell carcinoma cell line(YD-lOB) . 1'0 investigate the clifference 0 1' protei n ex press ion of cancel‘ cells influencecl by variable in vitro conditions. three different models were des ig necl ; Collagen gel- basecl ca ncer cell culture model devoid of fibroblasts(C) , Direct coτulture moclel(M2) composed of ca ncer cells beneath co ll agen gel embeclded with Swiss 31'3 fibroblasts ‘ and Indi rect co-culture model(Ml) with collagen layer betwecn cancel‘ cells and collagen gel with f lbroblasts Two-dimensional electrophoresis was performed to compa re t he diffe r ence of protein express ion pattern of ca ncer cells aznong three znodel systems. Protein identification was done by MALDI-TOF. As res ults ‘ pl'O te in express ion pat tem of cancel' cells was quite different between znonolayer cul ture and coll agen gel based cultu re. Aclditiona ll y. protein expression was different between culture models with fi broblasts and without fibroblasts a ncl between ind irect contact and direct contact of two cell types ‘ Among differentia l prot ei n spots. catheps in D WäS iuenLifï ed by MALDl• TOF Cathepsin D exprcssion was increased from C model to 11띠 and M2 model by West em blott ing. suggest ing that cathe psi n D expression may be activated by direct and indirect stimulation of stromal fï broblas ts F' rom these resul ts ‘ these models could be appropriate for EMI study and cathepsin D mi ght be incluced by fi broblasts s timulation
4,000원
4.
2005.12
구독 인증기관 무료, 개인회원 유료
Cultured normal human oral kera tinocyte(NHOK) & inunortalized human oral keratinocyte(IHOK) provide a valuable model in ce llular proliferation and differentiation after proper stimulation , And it is interesting to study these estab lished cell lines esca ping normal control on their growth and differentiation, SPRR1 is induced during t erminal differ entiation 0 1' human epiderma l kerat inocytes but is rarely in anaplastic cells of keratinocyte origin, But SPR1 expression has not yet been explained during differ entiation uf NHOK and Lransformed oral keraLinocyLes , The purpose of this study were to examine mHNA and protein expression of SPR1 in response to a known differentiation signal, calcium conc in NHOK, lHOK a nd oral SCC ce ll line(HN 4) , and to apply these results for investigating the molecular mecha nisms of tra nsformed cellular differentiation , Primary cultured NHOK, established IHOK and HN 4 cell line were cul tured in KBM bullet kit Preconfluency of NHOK as control group was used Under O, 15mM Ca++ conc(Precon, Postcon) , and 1, 2mM Ca++ conc(Pos tcon)‘ the insoluble final pellets were measured fo1' cornified cell envelope measurements, and RT- PCR for SPRR1 mRNA meas urement, and immunoblotting for SPRR1 protein measurements in tripli cate , resp ectively , The terminal different ia tion of cu ltured NHOK and IHOK was depend on calcium concentration, while HN4 cell line was not SPRR1 mRNA and protein expression of cultured NHOK showed the highest among cultured IHOK & HN 4 cell line in hi gher ca lcium condition , SPRR1 mRNA and protein expression of cultured IHOK showed higher‘ than tha t of HN 4 cell line in hjgher cacium condi tion , SPRH1 was expressed in differentiation of NHOK and IHOK t ransfected by E6/E7 genes but ra rely expressed in malignant oral keratinocytes , It suggested that SPRR1 ex pression as kera tinocyte terminal diff‘erent ia tion marker involved in cellular cornification would be differentially effected by immorta li zation and ca rcinogenic transforma tion
4,000원
5.
2005.12
구독 인증기관 무료, 개인회원 유료
Odontomas are the most common benign tumors of odontogenic origin characterized by their‘ slow growth, and a re cons ider ed to be developmental a nomalIes They consist of enamel, dentine, cementum and pulpal tissue and cons titue about 22% of all odontogeni c tumors The purpose of this study was to value clinicopathologic features of this kind 01 tumors‘ and to apply these results to make a pa ln of diagnosis and treatment in future, The 20 cases of odontomas between 1991 a nd 2004 subrn.i tted to Dept , of Oral Pathology of Dankook Univ, Dental Hos pital were used We analyzed theil‘ prev a lence‘ di s tributi on in gender , age of the pat ients , anatornic location. clinical manifestations and histopa thologic fea rtures Cli nical symptoms s howed delayed eruption(n=3) of either the deciduous or permanent tooth‘ mtra- 01 extraoral swelli ng(n =9). pain(n =2) , Of a ll the odontomas, 45% in the Mn & 55% in the Mx was seen There were 55% in the anter iosuperier sector & 25% i n the pos ter ioi nferior zone. while the rest in the upper molar region, COO showed 18,5 year s(r ange 6,4) , 60% 0[' diagnosed odontomas, incisor / canine area of mx, smaller(5-30mm) & unilocular. and mu l tip le radiopaque mini teeth s urroun따d by defined radiolucency, whi le CXO showed 30, 1 years(range 14 , 5) ‘ 40% of diagnosed odon tomas ‘ 1s t and 2nd molar of the mn, la rger(1O-60mrn) & unilocular undistinguished radiopaque mass and surrounded by ra di 이 uc e nt zo ne & a di s tin ct ra di opaque border, Both showed reduced enamel epithelium, enamel. dentin and cementum‘ di s play ing s ph eri al calcificat ions. and fibrous capsule as background , A.nd ghost cells were seen in 2 cases COO s howed hig hly orga nization & differenti ation, resembling a minitooth Each tooth was contained with co n nective tissuc sac CXO s howed haphazard organization, and was domi nated by dentin , displaying no resemblance a tooth, Through the definitive diagnos is of odonotmas on the basis of the clinicopath이 ogi c results, we should establish a plan in diagnosis and t rea tment of odontomas
4,000원
6.
2005.12
구독 인증기관 무료, 개인회원 유료
1'hi s s t u dy was pe rformed to investigate the osseointegration on the interface between bone and dental casting gold alloy's impla nts . Some inves tigators prese nted that only fi brous integratioJ1 in implant interface of precious met al im plants was occu red. 1'he mate ri a ls of dental implant must have biocompatibility and have no phY5ical 01' chemical s ide effect lmpla nts whi ch we re made of pure t itanium or titanium alloys had 50me chemical problem such as Galvanic current wi th s uprastru ctu re cur re ntly. So. we t hought that there was no problem if dental casting gold al1 0y’s impla nts had 5ucceed osseoin tegration. Thi s s tudy used 99%. 86%. 70% gold composition ìmplant as experimental group and tita niuITI implant as cont ral g rOllp. After 4th a nd 8th weeks of implant impLantation. experimental animals were saC l 나 i ce d and hi stologic sections we re made. All sections were examined by 8EM. PM. L8M. and EPMA. lmplants made of dental casting gold a ll oys occllrred good osseointegration as titanium implants. Osseointegr ation were not depend on the gold composit ion in implant groups ’ denta l casting gold al1oys. Both groll ps‘ osseointegration were 1TI0re completed in 8th weeks than 4th weeks . From t he a boving results. dental casting gold alloy's implants had induced similar osseointegrat ion to t h at 01" titan iu rn irnplants . So if we make implant and suprastructllre of dental casting gold alloys. Galvanic current and chemical co rrosio ns wOllld be sllppressed
4,200원
