We investigated the current status of institutional review boards (IRBs) that oversee research in dental hospitals. Eight hospitals, all of which had IRB, responded to our e-mail. The questions comprised two topics: IRBs and the clinical trials approved by them. The results showed that the average number of staff on IRBs of the 8 hospitals was 12.5. Furthermore, the proportion of dentists was the highest among the science committee members, with an average of 7.75, and the average number of non-dentists among the non-scientific members was 1.8. Regular IRBs convened meetings more than once a month, over the past year, or only if necessary.According to the approval status of clinical trials from 2016 to 2019, less than 50 studies accounted for 75%. The materials related to dental-implant procedures accounted for the highest quantity of materials used during clinical trials at 33.3%. The duration of 50% of the clinical trials ranged from more than 1 year to less than 2 years.Thus, based on the hypothesis that institutional reviews are currently conducted at dental hospitals and have raised issues and suggested improvements, we believe that IRBs will play an important role in dental hospitals, with more research conducted in dentistry in the future.
This study aimed to measure ramal lengths and angles on panoramic radiography applying a polar coordinate system for analyzing facial asymmetry within normal range. Panoramic radiographs taken from 15 males and 15 females (mean age 31.33±3.7 yrs in males and 28.87±2.72 yrs in females) with symmetric-looking faces were selected. The polar coordinate system, length of condylar and ramal height and angles between the ramus tangent and the connecting line of the most inferior point of bilateral orbital rim were measured from panoramic radiographic images. Bilateral differences in the ramal and condylar heights and angles were determined by asymmetric index. The polar coordinate applied for analyzing facial asymmetry uses length and angle measure. The normal range of facial asymmetry was measured using mean and standard deviation of asymmetry index of length and angle measure. A new analysis method using polar coordinate system on panoramic radiograph may provide more accurate analysis for facial asymmetry.
Nasopalatine duct cyst is a developmental non-odontogenic cyst caused by the entrapment of remnants during embryologic fusion. Only a few cases have reported the intraluminal amorphous calcification in these cysts. This case showed a well-demarcated, unilocular lesion containing calcifications, which were later turned out to be cartilage graft at previous surgery. We report here this case to emphasize the need for thorough medical history taking.
Verruciform xanthoma (VX) is a rare benign lesion of oral mucosa. It has an unclear etiology, and it mainly occurs in the oral cavity; however, it can be found in other locations as well. Oral VX is often clinically confused with papilloma, leukoplakia, condyloma, verruca vulgaris, verrucous carcinoma, or squamous cell carcinoma; therefore, biopsy is required to accurately diagnose this lesion. Our study reports four cases of oral VX with different clinical features but similar histopathological characteristics to emphasize the importance of differential diagnosis.