간행물
대한구강악안면병리학회지 KCI 등재 The Korean Journal of Oral and Maxillofacial Pathology
- 발행기관 대한구강악안면병리학회
- 자료유형 학술지
- 간기 격월간
- ISSN 1225-1577 (Print)2384-0900 (Online)
- 수록기간 1977 ~ 2026
- 주제분류 의약학 > 치의학 의약학 분류의 다른 간행물
- 십진분류KDC 515DDC 610
권호리스트/논문검색
제50권 제1호 (2026년 2월) 4건
1.
2026.02
구독 인증기관 무료, 개인회원 유료
Although vimentin is widely recognized as a mesenchymal marker, its expression in epithelial cells has been reported in several physiological and pathological conditions. The aim of this study was to investigate the immunoreactivity of vimentin in the epithelial component of benign odontogenic tumors. Immunohistochemistry for vimentin was performed in a total of 28 benign odontogenic tumors consisting of 11 WNT pathway-altered odontogenic tumors (WNT-OTs), 12 ameloblastomas, and 5 adenomatoid odontogenic tumors. All WNT-OTs (11/11), including calcifying odontogenic cyst, dentinogenic ghost cell tumor, and adenoid ameloblastoma, were focally positive for vimentin. Specifically, clear cells in close proximity to dentinoid were consistently positive, a subset of ghost cells were positive with varying degrees of intensity, but morular structures were negative. Two thirds of ameloblastomas (8/12) were focally positive for vimentin, more frequently in peripheral cells or the basal layer than in central cells or the upper layers, respectively. All adenomatoid odontogenic tumors (5/5) were focally positive for vimentin, especially in peripheral anastomosing strands and some cells adjacent to calcifications. Vimentin expression in epithelial cells is a common feature of benign odontogenic tumors. The intratumoral localization of vimentin in WNT-OTs may provide insights into the nature of their histologic components.
4,000원
2.
2026.02
구독 인증기관 무료, 개인회원 유료
Dyslipidemia, whose prevalence increases with aging, is widely recognized as a contributor to chronic inflammation. However, the association between serum lipoprotein indices reflecting lipid metabolism and osteoarthritis, an age-related disease, has not been fully elucidated. This study aimed to evaluate the relationship between serum lipoprotein indices, remnant cholesterol, and osteoarthritis among older adults. This cross-sectional study used raw data from the 2018–2020 Korea National Health and Nutrition Examination Survey (KNHANES). Serum lipid parameters total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) were analyzed. Remnant cholesterol was calculated as TC − (LDL-C + HDL-C). The association between serum lipid indices and osteoarthritis was assessed using multivariable regression analysis (logistic regression) adjusting for potential confounders. Among 296 participants aged ≥65 years, 89 (30.06%) reported having osteoarthritis. The osteoarthritis group had significantly higher remnant cholesterol (P < 0.05) and significantly lower HDL-C (P < 0.05) than the non-osteoarthritis group. There were no significant differences between groups in TC, LDL-C, or TG. In multivariable analyses, only remnant cholesterol showed a significant positive association with osteoarthritis risk (OR = 1.28, 95% CI: 1.08–1.54, P < 0.05). Although serum lipid abnormalities have been suggested as risk factors for osteoarthritis, the underlying epidemiologic mechanisms remain unclear. In this study, remnant cholesterol was significantly associated with osteoarthritis in older adults. Further studies are needed to clarify how metabolic factors such as hypercholesterolemia contribute to the development and progression of osteoarthritis. In addition, cholesterol reduction through lifestyle interventions—such as improving nutritional status and increasing physical activity—may represent a potential strategy for preventing and managing osteoarthritis in certain high-risk groups, and may help inform lifestyle guidance and identify novel targets for pharmacotherapy.
4,000원
3.
2026.02
구독 인증기관 무료, 개인회원 유료
The purpose of this study is to analyze the recent incidence rates of Behçet's disease using big data. Big data for this study was used for academic purposes in the 2019 to 2022 rare disease patient statistics from the Korea Disease Control and Prevention Agency (public domain source). A total of 3,886 newly diagnosed patients with Behçet's disease in Koreans from 2019 to 2022 were analyzed. In this study, the incidence of Behçet's disease was analyzed according to gender and age, and the incidence in the total population was also analyzed. The incidence rates of Behçet's disease from 2019 to 2022 were compared and analyzed at 1-year intervals. The incidence rate in men was in the 30% range, and in women, it was in the 60% range. The incidence of Behçet's disease in individuals over their 50s, approaching the elderly age group, was 42%. In the younger age group under 30, it was 16%. In this study, when analyzing the 4-year average incidence of Behçet's disease by age group from 2019 to 2022, it was found to be most common in people in their 40s at 24% over the past four years, followed by 50s at 22%, 30s at 17%, 60s at 14%, 20s at 12%, and 10s and 70s at 3%, showing a wide age distribution. This suggests that Behçet's disease can occur at any age.
4,000원
4.
2026.02
구독 인증기관 무료, 개인회원 유료
Necrotizing sialometaplasia (NSM) is a benign, self-limiting inflammatory condition of the salivary glands. Its clinical and histological resemblance to malignancies, such as squamous cell carcinoma and mucoepidermoid carcinoma, requires careful differentiation. While NSM predominantly affects the hard palate, its occurrence in atypical sites like the retromolar trigone is exceedingly rare and presents a significant diagnostic challenge. We report a case of NSM in a 30-year-old female presenting with a painful, indurated ulcer on the retromolar trigone. The lesion developed following a periodontal flap operation, suggesting an iatrogenic ischemic etiology. Despite an initial clinical suspicion of SCC, an incisional biopsy revealed extensive coagulative necrosis and prominent squamous metaplasia of the minor salivary glands. The diagnosis was confirmed by key histopathological features: the preservation of the underlying lobular architecture and the absence of cytologic atypia. The patient was managed conservatively, with complete resolution within six months. This case underscores the necessity of including NSM in the differential diagnosis of persistent gingival ulcers. Accurate histopathological recognition is paramount to avoid misdiagnosis and subsequent unnecessary, aggressive surgical intervention.
4,000원
