Stroke induces neuro-psychiatric symptoms as well as neural disorders. In oriental medical treatment of stroke, these neuro-psychiatric symptoms and motor․sensory nerve disorders are major and important points of differentiation of syndromes and major therapeutic aim for stroke patients. For looking at changes of neuro-psychiatric symptoms in stroke patients, we devided stroke patients into two groups by time after attack; group in 4 weeks (Group A) after attack, group more than 5 weeks (Group B). We examined them with SCL-90-R(Symptoms Check List-90-R), one of neuro-psy -chiatric examination tools, then the results as follows; In group A, phobic Anxiety was most high, and phobia anxiety, anxiety, psychoticism, hostility, depression, obsessive-compulsive, paranoid ideation and interpersonal sensitivity were located by score. In group B, phobic anxiety was most high, and depression, somatization, anxiety, psychoticism, interpersonal sensitivity, obsessive-compulsive, hostility, paranoid ideation were located by score. We recognized that all indexes of Group B including global severity index(GSI), positive symptom total(PST) and positive symptom distress index(PSDI) were higher than those of Group A. We suggest that the aim of treatment about stroke patients be made by considering changes of neuro-psychological symptoms.