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十二味寬中湯, 凉膈散火湯, 荊防瀉白散이 백서의 혈압 및 국소뇌혈류량에 미치는 영향

Effects of Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan on Blood Pressure and Regional Cerebral Blood Flow in Rats

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한국전통의학지 (The Journal of Traditional Korean Medicine)
한국전통의학연구소 (Research Center of Traditional Korean Medicine)
초록

1. Background and Purpose For many years, Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan have been used as a therapeutic agent in constitutional disease. The effects of three prescriptions on the vascular system is not well-known. The purpose of this study is to determine the effects of these prescriptions on blood pressure(BP) and regional cerebral blood flow(rCBF). 2. Methods I injected a vein of rat with extracts of Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan with five kinds of dose and measured BP and rCBF. 3. Results After injected Sibimikwanjungtang, BP was not changed but rCBF was increased in a dose-dependent manner. After injected Yangkyeoksanhwatang, BP was elevated and rCBF was increased in a dose-dependent manner. After injected Hyeongbangsabaeksan, BP was not changed but rCBF was increased in a dose-dependent manner.

저자
  • 李基珠(圓光大學校韓醫科大學四象醫學敎室) | 이기주
  • 金敬堯(圓光大學校韓醫科大學四象醫學敎室) | 김경요