Oral squamous cel1 carcinoma(OSCC) is the most common malignancy of head neck region. Typically OSCC cells s how persist ent invasion that frequently leads to local recurrence and distant lymphatic metastasls However, molecular mechanisms of invasion of OSCC remain poorly understood. Her e we identifi ed periostin, interferon induced transmembrane protein l (IF1TM1) and wingless-type MMTV integration site family, member 5B(WNT5B) , as invasion promoting molecules in OSCC by comparing gene expression profiles between a parent OSCC cell line(MSCC-l) and its highly invasive clone(MSCC-1nvl). Overexpression of periostin, IFITMl and WNT5B mRNAs were confirmed in MSCC-1nvl by RT-PCR. Transfection of these molecules promoted invasion of OSCC cells Moreover , siRNA t r eatment of these molecules suppressed invasion of cancer cells in vitro I nter estingly, Periostin, 1F1TMl and WNT5B were highly expressed in OSCCs in comparison with nonnal tissues. 1n an orthotopic mouse model of OSCC, periostin-overexpressing cells metas tasized spontaneously to cervical lymph nodes and t o t he lung through their aggressive invasiveness. These findings suggest that peri ostin, IFITMl and WNT5B play important roles for invasion and of OSCC and can be prognostic markers and therapeutic t argets of OSCC.

The use of low cost and ecofriendly adsorbent has been investigated as an alternative to the current expensive method of removing dyes from wastewater. Cow dung cakes were collected from the nearby village which was burnt in a muffle furnace at 500℃ to obtain the required ash. This paper deals with the removal of Reactive Blue 221, Acidoll Yellow 2GNL and Olive BGL which are mainly used in textile industry, from aqueous solution by cow dung ash without any pretreatment. The adsorption was achieved under different pH, adsorbate concentration and the applicability of Langmuir and Freundlich isotherms were examined.

As it is known, during the Second World War Greece has fought on the side of theallies and the end of the war found the country on the winners’side. However, thestruggle for authority right after 1945 was merciless and extremely difficult, as well asdangerous for the course of the country to the future. The political powers were dividedbetween the legal authorities that were represented by the king and formed the exiledgovernment on the one hand and the part of the resistance teams and the rebels of the leftthat had a soviet friendly direction on the other. Thus, the start of a civil war was just a matter of time. It finally started in 1947 andlasted for more than two years. The consequences were disastrous for the country’seconomy and decisive for the future course of Greece. The national army prevailed withthe help of, mostly, the English. Royal parliamentary democracy was established with aclear political turn to the west, as a completion and adaptation of the Agreement of theGreat Powers at Yalta. Art had a ‘similar’route. Dipolar, contradictory: conservative choices on the oneside, and a will for pioneering inspiration and perspective on the other side. The‘dominate’trend was first evident in sculpture and mainly in the public monuments. Theirconstruction aimed mostly at the public propaganda and at the promotion of the sovereignideology. On the one side we have the public sculptures composed of faces of contemporaryheroes or leading figures of the civic war and the national resistance. On the other side wehave monumental statues mainly that appeal to a ‘public’outside of the country’s bordersand mostly of the north borders, where there are countries with a communistic regime, likeBulgaria, Serbia and Albania. Their subject is derived from the heroic events of the BalkanWars (1912-1913) and ancient historical figures like Alexander the Great as the Greek armyleader, his father, Philippos II and Aristotle, who was of a north-Greek origin. The political message is twofold: on the one side the ‘inner enemy’the communiststhat were defeated and the promotion of the new liberal social system and on the otherside the north neighbours, which not only represent the East Block, but they also conspire the history and the culture of the Greeks. This is the way how the ‘Cold War’was resultedin a full and totalitarian expression in art.