This study was intended to compare with seismic fragility assessments for a low-rise RC piloti structure using the Capacity Spectrum Method (CSM) and the Incremental Dynamic Analysis (IDA). Distribution-parameters were estimated using the Method of Moments (MoM) and the Maximum Likelihood Estimation (MLE). For given limit states defined by FEMA 356, two seismic fragility assessments yielded different medians and dispersions: the CSM produced steeper in the slopes of fragility curves with smaller dispersions, whereas the IDA captured wider response scatters and broader dispersions. When fitting the fragility curves, the MLE scheme provided to well match with the empirical cumulative distribution function(CDF) than the MoM scheme, which understated dispersions.