This study proposes a wind power generation system designed to enhance energy self-sufficiency in high-rise buildings by integrating internal and external airflow sources. In such structures, external wind generated by building height and form and internal airflow induced by the stack effect coexist but move in different directions. This study introduces a system that collects and integrates five types of wind into a single, unified flow. Wind speed data were calculated using meteorological datasets and stack effect equations, and a prototype was designed using Autodesk Fusion360. CFD simulations were conducted to determine the combined wind speed at the outlet. Based on the simulated results, expected power output was calculated using wind power equations. The building energy model was created in DesignBuilder and simulated in EnergyPlus using default office building settings. The predicted annual wind energy generation is approximately 962,022.85kWh, covering 11.73% of the building’s total annual electricity use. The study demonstrates the potential for wind-integrated high-rise designs to contribute to energy autonomy.