Purpose: This study aimed to understand the COVID-19 vaccination experience of nursing students and explore its importance. Methods: A descriptive qualitative study and content analysis was conducted. The participants were 14 nursing students who expressed their rejection of COVID-19 vaccination. Data were collected through in-depth interviews from November 24, 2021, to January 30, 2022. Results: The COVID-19 vaccination experience of nursing students included four themes: “nostalgia for everyday life before COVID-19”, “hesitancy to get vaccinated against COVID-19”, “different thoughts about COVID-19 vaccination”, and “future direction of COVID-19 vaccination”. Conclusion: The COVID-19 vaccination experience of nursing students may be due to a lack of trust in COVID-19 vaccination. Therefore, accurate information about COVID-19 vaccination should be provided to lower the vaccination hesitancy of nursing students.