This paper proposes damage indices efficient on evaluating the seismic safety of cable-stayed bridges, especially dual-plane, cable-stayed bridges with H-type pylons. The research assumes that the location of accelerometers is already defined as given in the 2017 Ministry of the Interior and Safety (MOIS) guideline. In other words, the paper does not attempt to suggest optimal sensor location for the seismic safety evaluation of cable-stayed bridges. The proposed damage indices are based on those for building structures widely applied in the field already. Those include changes in natural frequencies and changes in relative lateral displacements. In addition, the study proposes other efficient damage indices as the rotation changes at the top of pylons and in the midspan of the girder system. Sensitivity analysis for various damage indices is performed through dynamic analysis using selected earthquake ground motions. The paper compares the effectiveness of the damage indices.