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        검색결과 2

        1.
        2024.06 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Hong Kong’s local writer Shu Xiangcheng has pioneered a course of local writing in Hong Kong literature that is unique to Hong Kong’s experience and composed entirely of local colours, and this has been recognised by critics. This article takes his long masterpiece The Sun Set as an example. Through his reproduction of Lingnan culture and Hong Kong’s regional features and people, we can see the picture of life with a strong Lingnan flavour sketched out by his delicate brushstrokes. From his reflections on urban expansion, we can see his “nostalgia” and “land-loving complex” with the port where he grew up, and his poetic and authentic language style, which provided valuable assets for the rise of local writers and the enrichment of Lingnan and Hong Kong literature later on. Unlike the vernacular writings of the Mainland and Taiwan in the same period, Shu Xiangcheng uses purely vernacular support to reproduce the reverse but romantic scenery of the ports at the same time when Hong Kong’s urban civilisation was progressing, in order to express his nostalgia for the disappeared ports in the expanding city, his praise for the simple folkways of the ports, and his critique of the city’s decadence and desires.
        4,900원
        2.
        2001.02 구독 인증기관 무료, 개인회원 유료
        Acetylcholinesterase(AChE) is an enzyme which hydrolyses acetylcholine into choline and acetate. Glucose and Adenosine-5'-Triphosphate(ATP) are the primary energy source for the brain and therefore defects in glucose metabolism and the mitochondrial system can affect cognitive function. The fact that the level of acetylcholine(ACh), neurotransmitter, glucose and ATP, are found to be decreased in the brain of Alzheimer patients has lead us to focus on the inhibition of AChE for the developmental research of the Alzheimer's disease(AD) treatment. In this paper we describe the effects of herbal medicine 9908(滌痰化瘀湯加減) in vitro and in vivo. As herb 9908 concentraion increased, the Vmax values of AChE from Electric eel were decreased, which showed that the activity of AChE in vitro was decreased. Also herb 9908 inhibit AChE activity in vivo. When herb 9908 was orally administrated to rats, amount of glucose and ATP which are energy source in metabolism, increase in brain and blood of rats. These result are also interesting in their effects for AD treatment compare with comercial drugs such as Cognex and Aricept. Furthermore, when considering the toxic problems of the Cognex and the Aricept, these oriental medicines could be very valuable medicine for treatment of AD. Abbreviation AD: Alzhemer's disease, AChE: acetylcholinesterase, ACh: acetylcholine, ATCh: acetylthiocholine, DTNB: 5,5‘-dithio-bis-2-nitrobenzoate, ATP: Adenosine-5'-triphosphate GAPD: Glyceraldehydephosphate dehydrogenase PGK : phosphoglycerate phosphokinase
        6,000원