Transforming growth factor-β (TGF-β) has been shown to have a positive effect on in vitro fertilization (IVF) and has been reported to stimulate meiosis at follicular level in variety of species. The study was designed to determine the expression patterns of TGF-β1, TGF-β receptors type Ⅰ, Ⅱ and Smads gene in bovine oocytes and embryos. TGF-β1 and their receptors were observed in the unfertilized oocytes. TGF-β1 and type Ⅱ receptor were not expressed at the blastocyst stage, however, only type I receptor was exclusively observed at the same stage. The blastocyst stage, in particular, showed high levels of mRNA expression patterns containing a TGF-β type Ⅰ receptor. The mRNA expression pattern of Smad 2 at all stages of embryonic development was similar in all respect with TGF-β1 type I receptor. On the contrary, Smad 3 and 4 were expressed with high and low level mRNA at the blastocyst stage. In conclusion, it is suggested that TGF-β signaling may be regarded as an important entity during the preimplantation embryo development.

This study explored measures to reduce noise applicable to Gimhae international airport centering on densely packed housing areas. Especially, as for measures to relieve noise damage on the densely packed housing areas in Gimhae-si, the noise reduction effect is expected to be doubled if the west runway (36L/18R) is used as the preferred runway for the 36 direction takeoff, as well as if the flight bypasses the densely packed housing areas by means of sophisticated navigation using the area navigation (RNAV) procedure based on performance-based navigation (PBN). Takeoff toward the south connects the flight path to the South Sea which has comparatively low noise impact, relieving noise damage on the densely packed housing areas (apartment complexes in Naeoe-dong of Gimhae-si, etc.) near the northern end of the runway. The operation of the runway displaced threshold is currently being implemented on the west runway (36L/18R) of Gimhae international airport. It has been found that swing landing in spring and summer when the wind blows from the south has a noise reduction effect on the noise sensitive areas at the side and end of the west runway (Gangdong-dong and Jukdong-dong of Gangseo-gu and Buram-dong of Gimhae-si, etc.).