We report results from an analysis of the X-ray archival data on MCG-2-58-22 obtained with Ginga, ROSAT and ASCA. By analyzing both short- and long-term light curves, we find clear time variations, ranging widely from, ~10 3 s to more than several years, in the X-ray energy range 0.1 - 10 keV. In addition, a flare is detected in 1991, overlaid on a gradual, secular flux decrease from 1979 to 1993; this flare has a time scale of about 1 year, and the X-ray flux increased by at least a factor of 3. The implications of these observational results are discussed in terms of accretion flow dynamics near a supermassive black hole.

Primary adenocarcinoma is a rare neoplasm of the urinary bladder, constituting approximately 2.5% of all primary bladder malignancies. Signet ring cell variant is even rarer, constituting approximately 0.5% to 2.0% of all primary carcinoma of the urinary bladder. However, glandular differentiation in the urinary bladder is relatively more common than primary adenocarcinoma of the urinary bladder. Therefore, diagnosis of primary adenocarcinoma of the urinary bladder can be very challenging, but of significant clinical importance. We report on a case of adenocarcinoma with mucinous and signet ring cell differentiation in the bladder dome in a 49-year-old female.