The aim of this research is to verify the moderating effect of logistics information systems (LIS) on inter-organizational collaboration (IOC) and performance. To achieve this aim, this research s pulled out the definitions of the variables from prior research and looked at the relationships between them. The population is the Korean shipping and logistics firms in the Republic of Korea, and a survey was carried out by members of liners and international freight forwarders. The questionnaires responded to by members of the sample firms were used as data for the analysis of this research. The reliability and validity of the data were tested by a factor analysis and the Cronbach’s alpha coefficient. In addition, the hypotheses of this research haves been verified using a multiple regression analysis. The results are as follows. LIS is confirmed as a factor in enhancing the relationship between IOC and performance. The firms perform IOC by LIS in supply chains and as a result, they can achieve high performance. This is explained by fit as moderation by Venkatraman (1989). In addition, the relationship between IOC and performance is explained by a resource-based view as is and the relationship between LIS and performance is also explained by a resource-based view. . Managers grasp customer needs and disseminate the needs to organizations using superior LIS, followed by high performance. Managers structure efficient supply chain processes through IOC between organizations and improve performance in the whole process through collaboration with the partners as well as departments. If managers want to achieve high performance through IOC, they should grasp their current level of LIS. This provides information; such as , what strategic decision making could improve their performance? The results of this research prove the moderating effect of LIS on IOC and performance and if managers focus on the moderating effect, they can improve performance.