This review examines the microstructural and mechanical properties of a Ti-6Al-4V alloy produced by wrought processing and powder metallurgy (PM), specifically laser powder bed fusion (LPBF) and hot isostatic pressing. Wrought methods, such as forging and rolling, create equiaxed alpha (α) and beta (β) grain structures with balanced properties, which are ideal for fatigue resistance. In contrast, PM methods, particularly LPBF, often yield a martensitic α′ structure with high microhardness, enabling complex geometries but requiring post-processing to improve its properties and reduce stress. The study evaluated the effects of processing parameters on grain size, phase distribution, and material characteristics, guiding the choice of fabrication techniques for optimizing Ti-6Al-4V performance in aerospace, biomedical, and automotive applications. The analysis emphasizes tailored processing to meet advanced engineering demands.

Background: The forward head posture acts as a factor that can cause various neurovascular and musculoskeletal dysfunctions. But searching for a study on quality of life for patient with forward head posture was challenging. Therefore, this study aims to find the factors that most affect the quality of life in patients with forward head posture. Objectives: The purpose of this study was to investigate the correlations between the cranio-vertebral angle (CVA), neck disability index (NDI), pain, and sternocleidomastoid (SCM) thickness of patients with forward head posture and the quality of life of the patients and to figure out important factors that affect the quality of life of the patients with forward head posture. Design: Cress-sectional study. Methods: To measure the CVA, the angle at which the visible protrusion of C7 and the ear bead were connected was measured, and the neck disorder index was evaluated using the Korean version of NDI. The degree of pain of the subject was measured using a visual-analog scale (VAS). The SCM thickness was measured using an ultrasound imaging device, and the quality of life was evaluated using the Korean version of the World Health Organization quality of life questionnaire (WHOQL-BREF). Results: A significant predictive model showing 88% explanatory power for the dependent variable was confirmed, with an appropriate regression equation being found. The factor that most affected patients' quality of life in the forward head posture was confirmed by the SCM thickness. Conclusion: When applying an intervention to improve a patient's quality of life for patient with forward head posture, an intervention method that improves the SCM thickness should be recommended.

한국에서 알스트로메리아(Alstroemeria)는 저온 작물로 난 방비 절감 효과가 있고 장식용 절화 소재로 꾸준히 소비되어, 일정 재배면적이 유지되고 있다. 본 연구는 알스트로메리아 ‘한에로스’의 기내 대량증식과 뿌리 발근 조건을 구명하고 무 균묘 생산 시스템을 구축하기 위해 수행했다. 기내 대량 증식 조건 구명 실험에는 Murashige and Skoog(MS) 배지(3% sucrose, 0.25% gelrite)에 BA 단용 처리(BA 0.25, 0.5, 0.75mg･L-1)와 NAA 0.2mg･L-1에 BA를 농도(BA 0.25, 0.5, 0.75mg･L-1)에 따라 혼용 처리하였다. 발근 조건 구명을 위 해 MS배지(3% sucrose, 0.25% gelrite)에 BA 0.25 mg･L-1 단용 처리와 BA 0.25mg･L-1에 NAA를 농도(NAA 0.1, 0.2, 0.3mg･L-1)에 따라 혼용 처리하였다. 뿌리줄기 증식 실험 결 과, 호르몬 첨가에 따른 생육차이는 뿌리줄기 수를 제외한 나 머지 부분에서 뚜렷하게 확인되었다. 단용 처리구 보다 혼용 처리구에서 많은 신초가 유도되었다. BA 0.5mg･L-1와 NAA 0.2mg･L-1 혼용 배지에서 가장 많은 1.43개의 신초가 유도되 었다. 발근 실험 결과, ‘한에로스’는 BA 0.25mg･L-1 와 NAA 0.3mg･L-1 혼용 배지에서 뿌리 수가 3.96개로 가장 많고, 뿌 리가 짧고 두꺼워 순화 과정 중에 뿌리 손실이 적었다. 또한, 순화 과정 중 묘가 고사하지 않았다. 종합적으로, ‘한에로스’ 는 BA 0.5mg･L-1와 NAA0.2 mg･L-1 혼용 배지에서 증식을 하는 것이 적절하며, BA 0.25mg･L-1와 NAA 0.3mg･L-1 혼 용 배지에서 발근 후 순화하는 것이 최적의 기내 배양 조건으 로 사료된다. 본 연구의 결과로 알스트로메리아 무균묘의 보 급 확대에 기여하고자 한다.

Emotional labor, characterized by a dysfunctional type of emotional regulation called surface acting, has detrimental psychological consequences on employees, including depression and social anxiety. Because such disorders exhibit psychological characteristics manifested through brain activation, previous studies have succeeded in distinguishing individuals with depression and social anxiety from healthy controls using their functional connectivity characteristics. However, it has not been established whether the functional connectivity characteristics associated with emotional labor are distinguishable. Thus, we obtained resting-state fMRI data from participants in the emotion labor (EL) group and control (CTRL) group, and we subjected their whole-brain functional connectivity matrices to a linear support vector machine classifier. Our analysis revealed that the EL and CTRL groups could be successfully distinguished on the basis of individuals' connectivity patterns, and confidence in the classification was correlated with the scores on the depression and social anxiety scales. These results are expected to provide insight on the neurobiological characteristics of emotional labor and enable the sorting of employees undergoing adverse emotional labor utilizing neurobiological observations.

IAEA has the right and obligation to verify the states’ commitments for safeguards under the comprehensive safeguards agreement and additional protocols. There are IAEA inspections such as PIV, DIV, RII, SNRI under these agreements. As part of the implementation of this mission, the IAEA inspectors perform the verification for the state’s accounting reports related the nuclear materials such as ICR, PIL, MBR. To do well this verification, the inspectors often use non-destructive analysis, which aims to measure attributes of the items during the inspections. This kind of an activity aims to detect the missing nuclear items or wrong things in the facility using nuclear materials. In general, NDA techniques use the neutron counting and gamma ray spectrometry. Besides, IAEA also performs several verification measures as follows. - C/S (Containment and Surveillance techniques) is to maintain the continuity of the knowledge by giving assurance that its containment remains unimpaired. - Unattended and remote monitoring is to transmit the data from onsite of the facility through the on-line system. - E/S (Environmental Sampling) is to detect the minute traces of nuclear materials by smearing some points in the on-site of the facility. Nowadays, the above mentioned techniques are important ways to increase the effectiveness of the safeguards approaches reducing IAEA actual costs. To strengthen the effectiveness and improve the efficiency of safeguards approaches, IAEA always develops and adopts the techniques and equipment for safeguards. Especially, IAEA seems to be concerned with the improvement and development of the non-destructive techniques and equipment in the fields of nuclear fuel cycle. IAEA develops the new techniques and equipment through the help of MSSP (Member States Support Programs). The IAEA defines the needs of safeguards and coordinates the support programs. After the IAEA tests and evaluates the techniques/equipment developed, IAEA decides whether to use the developed techniques and equipment during the inspection by the procedure of the IAEA quality assurance. This paper aims at studying the current changes of the IAEA equipment such as DCVD, NGSS and HCES.

The chelating agent and cellulose generated during the operating and decommissioning of a NPP’s form organic complexing compounds. That is accelerate the migration of radionuclide and have a bad influence of LILW disposal site. In this study, the GoldSim (RT module) program was used for the effects of radionuclide migration by organic complex compounds as described above. A scenario was derived for evaluation, and a conceptual design (Concept Art) of the GoldSim model was performed. 1) Derivation of the scenario. For the scenario, we selected a groundwater flow scenario in which groundwater flows in and radionuclides flow out after a lapse of time after the operation of the LILW disposal site in Gyeongju is closed. The inflowing groundwater comes into contact with radioactive waste and the radionuclides dissolve. The dissolved nuclides move past the drum and out of the disposal vessel due to the advection phenomenon. Radionuclides spilled from the disposal vessel pass through the silo internal filler (crushed stone) and reach the engineering barrier concrete. Radionuclides from degraded concrete are scenarios that move along the flow of groundwater to the near and far. 2) Radionuclide migration concept design. The radionuclide movement section was largely designed with Inner (Inside the silo), Near and Far. (A) Inner (Inside the silo) This section is where radionuclides move from the radiation source to the engineering barrier (silo). The detailed migration path was designed to allow radioactive nuclides to flow out and move to waste drums, solidified matrix of indrum, disposal vessel fillers, disposal vessels, silo fillers (crushed stones), and engineered barriers (concrete). The LILW disposal site in Gyeongju has a total of 6 silos. Each of the 6 silos was modeled and designed in consideration of the structural information and positional impact. (B) Near & Far. In generally design, the near is form source term to engineered barrier and far is beyond the engineered barrier. In this study, the near and far designed by radionuclide in the section from the beyond the engineering barrier (silo) to the sea through the groundwater flow through the natural rock. Especially in the case of near, the design was made by applying the position of the natural rock sampling drill hole.

The CC chemokine receptor 5 (CCR5) is a G protein-coupled receptor that regulates chemotaxis and effector functions of immune cells. It also serves as the major co-receptor for the entry of human immunodeficiency virus (HIV). Recently, CCR5 inhibitors have been developed and used for the treatment or prevention of HIV infections. Additionally, it has been identified that CCR5 controls bone homeostasis by regulating osteoclastogenesis and the communication between osteoblasts and osteoclasts. However, the effects of CCR5 inhibition on bone tissue in elderly patients are unknown. This study aimed to examine the bone phenotype of aged CCR5 knockout (KO) mice. Femoral and tibial bones were isolated from 12-month and 18-month old wild-type (WT) and CCR5 KO mice, and microcomputed tomography and histology analyses were performed. Twelve-month-old CCR5 KO mice exhibited a decreased trabecular bone mass and cortical bone thickness in both femoral and tibial bones compared with agematched WT mice. Eighteen-month-old mice also showed a decreased trabecular bone mass in femurs compared with control WT mice, but not in tibial bones. Unlike in 12-month-old mice, the cortical margin of femurs and tibias in 18-month-old mice were rough, likely because they were aggravated by the deficiency of CCR5. Overall, our data suggest that the deficiency of CCR5 with aging can cause severe bone loss. When CCR5 inhibitors or CCR5 inactivating technologies are used in elderly patients, a preventive strategy for bone loss should be considered.

We investigated the neural representation of reward probability recognition and its neural connectivity with other regions of the brain. Using functional magnetic resonance imaging (fMRI), we used a simple guessing task with different probabilities of obtaining rewards across trials to assay local and global regions processing reward probability. The results of whole brain analysis demonstrated that lateral prefrontal cortex, inferior parietal lobe, and postcentral gyrus were activated during probability-based decision making. Specifically, the higher the expected value was, the more these regions were activated. Fronto-parietal connectivity, comprising inferior parietal regions and right lateral prefrontal cortex, conjointly engaged during high reward probability recognition compared to low reward condition, regardless of whether the reward information was extrinsically presented. Finally, the result of a regression analysis identified that cortico-subcortical connectivity was strengthened during the high reward anticipation for the subjects with higher cognitive impulsivity. Our findings demonstrate that interregional functional involvement is involved in valuation based on reward probability and that personality trait such as cognitive impulsivity plays a role in modulating the connectivity among different brain regions.